Publications 2015-2016

  • Pericyclic Reactions of Azafulvenium Methides Bearing Internal Dipolarophiles: Synthesis of Chromene and Chromane Derivatives, Fernanda M. Ribeiro Laia, Maria I. L. Soares, Clara S. B. Gomes, and Teresa M. V. D. Pinho e Melo, Eur. J. Org. Chem. 2015, 1341-1354 [DOI: 10.1002/ejoc.201403407].
  • Novel approach to bis(indolyl)methanes: de novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties, Carla Grosso, Ana Lúcia Cardoso,  Américo Lemos, João Varela, Maria João Rodrigues, Luísa Custódio, Luísa Barreira, Teresa M.V.D. Pinho e Melo,  Eur. J. Med. Chem. 2015, 93, 9-15 [http://dx.doi.org/10.1016/j.ejmech.2015.01.050].
  • Thermolysis of 1-(Thiophen-2-yl)-1H-Tetrazoles: One Way to Thiophene-fused Imidazoles and Pyrimidines, Maria I. L. Soares, Ana C. F. de Lyra,  Marta S. C. Henriques, José A. Paixão, Teresa M. V. D. Pinho e Melo, Tetrahedron 2015,71, 3343-3350 [doi:10.1016/j.tet.2015.03.102].
  • Synthesis and Thermal Reactivity of Thiazolo[3,4-a]benzimidazole-2,2-dioxides: Approach to 1H-Benzo[d]imidazoles via Novel Benzo-2,5-diazafulvenium Methides, Maria I. L. Soares, Teresa M. V. D. Pinho e Melo, Tetrahedron 2015, 71, 4227-4235 [http://dx.doi.org/10.1016/j.tet.2015.04.079].
  • Synthesis and Reactivity of Aziridines with Internal Dipolarophiles: an Approach to 1,4-Dihydrochromeno[4,3-b]pyrroles and 3-Methylenechromano[4,3-b]pyrroles, Fernanda M. Ribeiro Laia, Teresa M. V. D. Pinho e Melo, Synthesis 2015, 47, 2781-2790 [DOI: 10.1055/s-0034-1378717].
  • Synthesis of Chiral Hexacyclic Steroids via [8π+2π] Cycloaddition of Diazafulvenium methides, Susana M. M. Lopes, Cátia F. O. Correia, Sandra C. C. Nunes, Nelson A. M. Pereira, Ana R. F. Ferreira, Emanuel P. Sousa, Clara S. B. Gomes, Jorge A. R. Salvador, Alberto A. C. C. Pais, Teresa M. V. D. Pinho e Melo, Org. Biomol. Chem. 2015, 13, 9127-9139 [DOI: 10.1039/c5ob01110h].
  • Exploring the Chemistry of Furans: Synthesis of Functionalized Bis(furan-2-yl)methanes and 4,5-Dihydro-1H-pyrazoles, Susana M. M. Lopes, Marta S. C. Henriques, José A. Paixão, Teresa M. V. D. Pinho e Melo, Eur. J. Org. Chem. 2015, 6146–6151 [http://dx.doi.org/10.1002/ejoc.201500878].
  • Inter-regional variation on leaf surface defenses in native and non-native Centaurea solstitialis plants, Gastón J. Sotes, Lohengrin A. Cavieres, Daniel Montesinos, António Pereira Coutinho, Walter José Peláez, Susana M. M. Lopes, Teresa M. V. D. Pinho e Melo, Biochemical Systematics and Ecology 2015, 62, 208-218 [http://dx.doi.org/10.1016/j.bse.2015.09.003].
  • Novel 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridine Fused Chlorins as Very Active Photodynamic Agents for Melanoma Cells, Nelson A. M. Pereira, Mafalda Laranjo, Marta Pineiro, Arménio C. Serra,  Kathleen Santos, Ricardo Teixo, Ana Margarida Abrantes, Ana Cristina Gonçalves, Ana Bela Sarmento Ribeiro, M. Filomena Botelho, Teresa M. V. D. Pinho e Melo, Eur. J. Med. Chem. 2015, 103, 374-380 [DOI: 10.1016/j.ejmech.2015.08.059].
  • Synthesis of New 2-Halo-2-(1H-Tetrazol-5-yl)-2H-Azirines via a non-Classical Wittig Reaction, Ana L. Cardoso, Carmo Sousa, Marta S. C. Henriques, José A. Paixão, Teresa M. V. D. Pinho e Melo, Molecules 2015, 20 (12), 22351-22363 [doi:10.3390/molecules201219848].
  • Bis-furans as novel transthyretin stabilizers and amyloid inhibitors, Carlos J. V. Simões, Zaida L. Almeida, Dora Costa, Catarina S. Jesus, Ana L. Cardoso, Maria R. Almeida, Maria J. Saraiva, Teresa M. V. D. Pinho e Melo, Rui M. M. Brito, Eur. J. Med. Chem. 2016, 121, 823-840 [doi:10.1016/j.ejmech.2016.02.074].
  • Reactivity of 1-Arylnitrosoethylenes Towards Indole Derivatives,Susana M. M. Lopes, Sandra C. C. Nunes, Cátia C. Caratão, Alberto A. C C. Pais, Teresa M. V. D. Pinho e Melo,Monatsh. Chem. 2016,  147 (9), 1565-1573  [DOI: 10.1007/s00706-016-1763-1]-Monatshefte für Chemie - Chemical Monthly
  • Chemistry of Aza- and Diazafulvenium Methides in Heterocyclic Synthesis,Teresa M. V. D. Pinho e Melo, Pure Appl. Chem. 2016, 88, 457-475. [Article-DOI: 10.1515/pac-2016-0404].
  • D-Penicillamine- and L-Cysteine-Derived Thiazolidine Catalysts: A Highly Efficient Approach to Both Enantiomers of Secondary Alcohols,M. Elisa Silva Serra*, Dora Costa, Dina Murtinho, Nélia Tavares, Teresa M. V. D. Pinho e Melo,Tetrahedron 2016, 72, 5923-5927 [http://dx.doi.org/10.1016/j.tet.2016.08.036].
  • 1H-Tetrazol-5-yl)-Allenes: Building Blocks for Tetrazolyl-Heterocycles, Ana L. Cardoso, Marta S. C. Henriques, José A. Paixão, Teresa M. V. D. Pinho e Melo,J. Org. Chem. 2016, 81, 9028-9036 [DOI: 10.1021/acs.joc.6b01679].
  • Synthesis of Thieno[2,3-d]pyrimidines via Microwave-Assisted Thermolysis of 1-(Thiophene-2-yl)-1H-tetrazoles, Maria I. L. Soares, Teresa M. V. D. Pinho e Melo, Rui Fausto,ChemistrySelect 2016, 1, 4591–4595 [DOI: 10.1002/slct.201601196].