Páginas pessoais

Patricia O. Ferreira, Amanda C. Almeida, Giovanna de P. Costa, Carolina Torquetti, João A. Baptista, M. Ermelinda S. Eusébio, Flavio J. Caires, Ricardo A. E. Castro

Journal of Pharmaceutical Sciences 112 (2023) 2230-2239

https://doi.org/10.1016/j.xphs.2023.03.003

[50]

Pharmaceutical nanococrystal synthesis: a novel grinding approach

João A. V. Santos, João A. Baptista, Inês C. Santos, Teresa M. R. Maria, João Canotilho, Ricardo A. E. Castro, M. Ermelinda S. Eusébio

CrystEngComm 24 (2022) 947-961

Capa de revista

https://doi.org/10.1039/D1CE00407G

[49]

Dihydrofolate reductase inhibitors: the pharmacophore as a guide for co-crystal screening

João A. Baptista, Mário T.S. Rosado, Ricardo A.E. Castro, António O.L. Évora, Teresa M.R. Maria, Manuela Ramos Silva, João Canotilho, M. Ermelinda S. Eusébio

Molecules 26 (2021) 6721

https://doi.org/10.3390/molecules26216721

[48]

Polymorphic cocrystals of the antimalarial drug pyrimethamine: Two case studies

João A. Baptista, Ricardo A. E. Castro, Mário T. S. Rosado, Teresa M. R. Maria, M. Ramos Silva, João Canotilho, and M. Ermelinda S. Eusébio

Crystal Growth & Design, 21 (2021) 3699-3713

https://doi.org/10.1021/acs.cgd.1c00005

[47]

Ethosomes as nanocarriers for the development of skin delivery formulations

Ana Cláudia Paiva-Santos, Ana Luísa Silva, Catarina Guerra, Diana Peixoto, Miguel Pereira-Silva, Mahdi Zeinali, Filipa Mascarenhas-Melo, Ricardo Castro, Francisco Veiga

Pharmaceutical Research 38 (2021) 947-970

https://doi.org/10.1007/s11095-021-03053-5

[46]

At-line monitoring of salification process of the antiretroviral lamivudine-saccharinate salt using FT-MIR spectroscopy with multivariate curve resolution

Sarmento J. Mazivila, Ricardo Castro, Joao Leitao, Joaquim Esteves da Silva

Vibrational Spectroscopy 106 (2019) xx-xx

https://doi.org/10.1016/j.vibspec.2019.102992

[45]

Metoprolol: solid forms of a top selling antihypertensive

Mariani A. Ciciliati, M. Ermelinda S. Eusébio, Manuela Ramos Silva, Éder Tadeu Gomes Cavalheiro, Ricardo A. E. Castro

CrystEngComm 21 (2019) 4319 - 4328

https://doi.org/10.1039/C9CE00700H

[44]

Polymorphism of 1,3-cyclohexanediols. Molecular structure and plastic crystal formation of cyclohexanediol isomers

Teresa Maria, Mário T. S. Rosado, Melodia F. Oliveira, Suse S. Bebiano, Ricardo Castro, Ewa Juszyńska-Gałązka, Manuela Ramos Silva, João Canotilho, M. Ermelinda S. Eusébio

CrystEngComm 21 (2019) 3395 - 3408

https://doi.org/10.1039/C9CE00186G

[43]

Polymorphism of Gemfibrozil: Investigation by thermal and spectroscopic methods

Bruno Holanda, Gilbert Bannach, Ermelinda Eusebio, Manuela Ramos Silva, Ricardo Castro

Thermochimica Acta 675 (2019) 113-118

https://doi.org/10.1016/j.tca.2019.03.026

[42]

At-line green synthesis monitoring of new pharmaceutical co-crystals lamivudine:theophylline polymorph I and II, quantification of polymorph I among its APIs using FT-IR spectroscopy and MCR-ALS

Sarmento J. Mazivila, Ricardo A. E. Castro, João M. M. Leitão, Joaquim C. G. Esteves da Silva

Journal of Pharmaceutical and Biomedical Analysis 169 (2019) 235-244

https://doi.org/10.1016/j.jpba.2019.03.014

[41]

Lamotrigine: Design and synthesis of new multicomponent solid forms

António O.L.Évora, Ricardo A.E.Castro, Teresa M.R.Maria, M.Ramos Silva, JoãoCanotilho, M. Ermelinda S.Eusébio

European Journal of Pharmaceutical Sciences 129 (2019) 148-162

https://doi.org/10.1016/j.ejps.2019.01.007

[40]

Thermal studies, degradation kinetic, equilibrium solubility, DFT, MIR, and XRPD analyses of a new cocrystal of gemfibrozil and isonicotinamide

Bruno B. C. Holanda, Rafael T. Alarcon, Caroline Gaglieri, Aguinaldo R. de Souza, Ricardo A. E. Castro, Paulo C. P. Rosa, Débora J. A. Tangerino, Gilbert Bannach

Journal of Thermal Analysis and Calorimetry 136 (2019) 2049–2062

https://doi.org/10.1007/s10973-018-7873-8

[39]

Investigation of thermal degradation products of mebendazole by thermal and spectroscopic analysis

Bruno B. C. Holanda, Rafael T. Alarcon, Renan B. Guerra, Daniel Rinaldo, Fabiola C. R. Spazzini, Ricardo A. E. Castro, Gilbert Bannach

Journal of Analytical and Applied Pyrolysis, 135 (2018) 76-84

https://doi.org/10.1016/j.jaap.2018.09.017

[38]

Physicochemical, thermal, crystallographic and morphological properties of biodynamic black rice starch, and of residual fractions from aqueous extraction

Vivian C. Ito, Egon Schnitzler, Ivo Mottin Demiate, Maria Ermelinda S. Eusébio, Luiz Gustavo Lacerda, Ricardo A. E. Castro

Starch 70 (2018) 1700348 (1-7)

https://doi.org/10.1002/star.201700348

[37]

Synthesis, physicochemical and optical properties of bis-thiosemicarbazone functionalized graphene oxide

Santosh Kumar, Mohmmad Y. Wani, Claudia T. Arranja, Ricardo A.E. Castro, José A. Paixão, Abilio J.F.N. Sobral

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 188 (2018) 183-188

https://doi.org/10.1016/j.saa.2017.06.045

[36]

Levetiracetam + nonsteroidal anti-inflammatory drug binary systems: a contribution to the development of new solid dosage forms

Sara M.T. Machado, Ricardo A.E. Castro, Teresa M.R. Maria, João Canotilho, M. Ermelinda S. Eusébio

International Journal of Pharmaceutics 533 (2017) 1-13

https://doi.org/10.1016/j.ijpharm.2017.09.012

[35]

Thermoanalytical study of sweetener myo-inositol: α and β polymorphs

Rafael Turra Alarcon, Caroline Gaglieri, Flávio Junior Caires, Aroldo Geraldo Magdalena, Ricardo A. E. Castro, Gilbert Bannach

Food Chemistry 237 (2017) 1149-1154

https://doi.org/10.1016/j.foodchem.2017.06.072

[34]

Double-tailed long chain BODIPYs - Synthesis, characterization and preliminary studies on their use as lipid fluorescence probes

Cláudia T. Arranja, António Aguiar, Telma Encarnação, Sofia M. Fonseca, Licínia L.G. Justino, Ricardo A.E.Castro, Andrew Benniston, Anthony Harriman, Hugh D.Burrows, Abilio J.F.N.Sobral

Journal of Molecular Structure 1146 (2017) 62-69

http://dx.doi.org/10.1016/j.molstruc.2017.05.119

[33]

Binary phase diagrams of pyridinecarboxamide isomers.

Ana M. Cortesão, João G. Henriques, Ricardo A. E. Castro, Teresa M. R. Maria, João Canotilho, M. Ermelinda S. Eusébio

Journal of Thermal Analysis and Calorimetry 130 (2017) 1727-1733

Impact Factor:

http://dx.doi.org/10.1007/s10973-017-6474-2

http://rdcu.be/thjO

[32]

A combined approach using differential scanning calorimetry with polarized light thermomicroscopy in the investigation of ketoprofen and nicotinamide cocrystal

G.L. Perpétuo, G.O. Chierice, L.T. Ferreira, T.F.C. Fraga-Silva, J. Venturini, M.S.P. Arruda, G. Bannach, R.A.E. Castro

Journal of Thermal Analysis and Calorimetry 651 (2017) 1-10

Impact Factor:

http://dx.doi.org/10.1016/j.tca.2017.02.014

[31]

Co-crystals of diflunisal and isomeric pyridinecarboxamides – a thermodynamics and crystal engineering contribution

Antonio O.L. Evora, Ricardo Castro, Teresa Maria, Manuela Ramos Silva, Joop H. ter Horst, João Canotilho, M. Ermelinda S. Eusébio

CrystEngComm 18 (2016) 4749-4759

Impact Factor: 4,03

http://dx.doi.org/10.1039/C6CE00380J

[30]

Studying the thermal decomposition of carvedilol by coupled TG-FTIR

R. C. Gallo, A. P. G. Ferreira, R. A. E. Castro, E. T. G. Cavalheiro

Journal of Thermal Analysis and Calorimetry 123 (2016) 2307-2312

Impact Factor: 1.953

http://dx.doi.org/10.1007/s10973-015-4931-3

[29]

Structural evidence of polymorphism and conformational isomorphism of a somewhat flexible molecule: m-anisic acid

Pedro S. Pereira Silva, Ricardo A. E. Castro, Elodie Melro, Manuela Ramos Silva, Teresa M. R. Maria, João Canotilho, M. Ermelinda S. Eusébio

Journal of Thermal Analysis and Calorimetry 120 (2015) 667-677

Impact Factor: 2.206

http://dx.doi.org/10.1007/s10973-014-4289-y

[28]

Molecular Structure and Polymorphism of a Cyclohexane Diol: trans-1,4-cyclohexanedimethanol

Mário T. S. Rosado, Teresa M. R. Maria, Ricardo A. E. Castro, João Canotilho, Manuela Ramos Silva and M. Ermelinda S. Eusébio

CrystEngComm 16 (2014) 10977-10986

Impact Factor: 3.858

http://dx.doi.org/10.1039/C4CE01211A

[27]

Synthesis and polymorphism evaluation of the 3,5-bis(decyloxy)benzaldehyde

Cláudia T. Arranja, Mariana Marcos, Manuela R. Silva, M. Ermelinda S. Eusébio, Ricardo A. E. Castro and Abílio J. F. N. Sobral

Journal of Thermal Analysis and Calorimetry 117 (2014) 1375-1383

Impact Factor: 1.982

http://dx.doi.org/10.1007/s10973-014-3904-2

[26]

A thermodynamic based approach on the investigation of a diflunisal pharmaceutical co-crystal with improved intrinsic dissolution rate

António O. L. Évora, Ricardo A. E. Castro, Teresa M. R. Maria, M. Ramos Silva, J. H. ter Horst, João Canotilho, M. Ermelinda S. Eusébio

International Journal of Pharmaceutics, 466 (2014) 68-75

Impact Factor: 3.458

http://dx.doi.org/10.1016/j.ijpharm.2014.02.048

[25]

Polymorphism of cis-1,4-cyclohexanediol, a new plastic crystal former. Considerations on isomeric cyclohexanediols plastic crystal forming abilities.

Suse V. S. Bebiano, Mário T. S. Rosado, Ricardo A. E. Castro, M. Ramos Silva, João Canotilho, Teresa M. R. Maria, M. Ermelinda S. Eusébio

Journal of Molecular Structure 1078 (2014) 10-19

Impact Factor: 1.404

http://dx.doi.org/10.1016/j.molstruc.2014.02.008

[24]

Nanostructuring of the conjugated polyelectrolyte poly[9,9-bis(4-sulfonylbutoxyphenyl)fluorene-2,7-diyl-2,2'-bithophene] in liquid crystalline C12E4 in bulk water and aligned thin films

Matti Knaapila, Sofia M Fonseca, Beverly Stewart, Mika Torkkeli, Jan Perlich, Swapna Pradhan, Ullrich Scherf, Ricardo Castro and H D Burrows

Soft Matter, 10 (2014) 3103 - 3111

Impact Factor: 3.909

http://dx.doi.org/10.1039/C4SM00092G

[23]

Thermoanalytical study of nimesulide and their recrystallization products obtained from solutions of several alcohols

D. A. Gálico, G. L. Perpétuo, R. A. E. Castro, O. Treu-Filho, A. O. Legendre, M. S. Galhiane, G. Bannach

Journal of Thermal Analysis and Calorimetry 115 (2014) 2385-2390

Impact Factor: 1.752

http://dx.doi.org/10.1007/s10973-013-3294-x

[22]

Structural characterization of solid trivalent metal dodecyl sulfates: from aqueous solution to lamellar superstructures

Rui F. P. Pereira, Artur J. M. Valente, Hugh D. Burrows, V. de Zea Bermudez, Rui A. Carvalho and Ricardo A. E. Castro

RSC Advances 3 (2013) 1420-1433

Impact Factor: 3.842

http://dx.doi.org/10.1039/c2ra21906a

[21]

Polymorphism and melt crystallisation of racemic betaxolol, a beta-adrenergic antagonist drug

Teresa M. R. Maria, Ricardo A. E. Castro, M. Ramos Silva, M. Luísa Ramos, Licínia L. G. Justino, Hugh D. Burrows, João Canotilho, M. Ermelinda S. Eusébio

Journal of Thermal Analysis and Calorimetry 111 (2013) 2171-2178

Impact Factor: 1.752

http://dx.doi.org/10.1007/s10973-012-2765-9

[20]

Thermal behavior of some antihistamines

G. L. Perpétuo, D. A. Gálico, R. A. Fugita, R. A. E. Castro, M. E. S. Eusébio, O. Treu-Filho, A. C. M. Silva and G. Bannach

Journal of Thermal Analysis and Calorimetry 111 (2013) 2019-2028

Impact Factor: 1.752

http://dx.doi.org/10.1007/s10973-012-2247-0

[19]

Resolved structures of two picolinamide polymorphs. Investigation of the dimorphic system behaviour under conditions relevant to co-crystal synthesis

António O. L. Évora, Ricardo A. E. Castro, Teresa M. R. Maria, M. Ramos Silva, João Canotilho, M. Ermelinda S. Eusébio

CrystEngComm 14 (2012) 8649-8657

Impact Factor: 3.842

http://dx.doi.org/10.1039/c2ce26244d

[18]

Naproxen co-crystals with pyridinecarboxamide isomers

Esteves de Castro, R.A.; Ribeiro, João; Maria, Teresa; Ramos Silva, Manuela; Yuste-Vivas, Consuelo; Canotilho, João; Eusébio, Ermelinda

Crystal Growth & Design 11 (2011) 5396-5404

Impact Factor: 4.389

http://dx.doi.org/10.1021/cg2009946

[17]

A new pharmaceutical co-crystal: (S)-naproxen-isonocotinamide

Consuelo Yuste-Vivas, Manuela Ramos Silva, Ricardo A. E. Castro, João D. B. Ribeiro, Teresa M. R. Maria, João Canotilho, M. Ermelinda S. Eusébio

Acta Cryst. A (2011) A67, C569-C570

Impact Factor: 2.07

http://dx.doi.org/10.1107/S010876731108559X

[16]

Pyrazinamide-diflunisal: A new dual-drug co-crystal

António O.L. Évora , R.A. Esteves de Castro , Teresa Roseiro Maria , Mário Túlio dos Santos Rosado , Manuela Ramos Silva , Ana Matos Beja , João Canotilho , and Ermelinda S. Eusébio

Crystal Growth & Design 11 (2011) 4780-4788

Impact Factor: 4.389

http://dx.doi.org/10.1021/cg200288b

[15]

β-Phase Formation of Poly(9,9-dioctylfluorene) Induced by Liposome Phospholipid Bilayers

Maria José Tapia, Maria Monteserín, Hugh D. Burrows, J. Sérgio Seixas de Melo, João Pina, Ricardo A. E. Castro, Sonia Garcia, and Joan Estelrich

Journal of Physical Chemistry B, 115 (2011) 5794-5800

Impact Factor: 3.471

http://dx.doi.org/10.1021/jp2010666

[14]

The structure of betaxolol studied by infrared spectroscopy and natural bond orbital theory

J. Canotilho, R.A.E. Castro

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 76 (2010) 395-400

Impact Factor: 1.510

http://dx.doi.org/10.1016/j.saa.2010.03.038

[13]

Polymorphism of trans-1,4-cyclohexanediol: conformational isomorphism

Teresa Maria; R.A. Esteves de Castro; Suse S. Bebiano; Manuela Ramos Silva; Ana Matos Beja; João Canotilho; Ermelinda Eusébio

Crystal Growth & Design 10 (2010) 1194-1200

Impact Factor: 4.215

http://dx.doi.org/10.1021/cg901160v

[12]

Thermal analysis and crystallization from melts: beta-adrenergic compounds

J. Canotilho, R. A. E. Castro, M. T. S. Rosado, S. C. C. Nunes and J. S. Redinha

Journal of Thermal Analysis and Calorimetry 100 (2010) 423-429

Impact Factor: 1.63

http://dx.doi.org/10.1007/s10973-009-0645-8

[11]

A New Insight into Pyrazinamide Polymorphic Forms and their Thermodynamic Relationships

Ricardo A. E. Castro, Teresa M. R. Maria, António O. L. Évora, Joana C. Feiteira, M. Ramos Silva, A. Matos Beja, João Canotilho, and M. Ermelinda S. Eusébio

Crystal Growth & Design 10 (2010) 274-282

Impact Factor: 4.215

http://dx.doi.org/10.1021/cg900890n

[10]

Synthesis, spectroscopy, photophysics and thermal behaviour of stilbene-based triarylamines with dehydroabietic acid methyl ester moieties

B. Gigante, M. A. Esteves, N. Pires, M.L. Davies, P. Douglas, S. M. Fonseca, H. D. Burrows, Ricardo A.E. Castro, J. Pina and J. Seixas de Melo

New Journal of Chemistry 33 (2009) 877-885

Impact Factor: 2.651

http://dx.doi.org/10.1039/b815711a

[9]

A study of the structure of the pindolol based on infrared spectroscopy and natural bond orbital theory
Ricardo A. E. Castro, João Canotilho, Sandra C. C. Nunes, M. Ermelinda S. Eusébio, J. Simões Redinha
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 72 (2009) 819–826
Impact Factor: 1.511
http://dx.doi.org/10.1016/j.saa.2008.11.026

[8]

The structure of betaxolol from single-crystal X-ray diffraction and natural bond orbital analysis
João Canotilho, Ricardo A. E. Castro, Mário T. S. Rosado, M. Ramos Silva, A. Matos Beja, J. A. Paixão, J. Simões Redinha

Journal of Molecular Structure 891 (2008) 437-442

Impact Factor: 1.486

http://dx.doi.org/10.1016/j.molstruc.2008.04.029

[7]

Interactions between hairy rod anionic conjugated polyelectrolytes and nonionic alkyloxyethylene surfactants in aqueous solution: Observations from cloud point behavior

Sofia M. Fonseca, M. Ermelinda Eusébio, Ricardo Castro, Hugh D. Burrows, Maria José Tapia, Ulf Olsson
Journal of Colloid and Interface Science 315 (2007) 805–809

Impact Factor: 2.309

http://dx.doi.org/10.1016/j.jcis.2007.07.006

[6]

Solvation enthalpy and the thermodynamics of hydration of trans-cyclohexyl-1,4-diamine and cis-cyclohexyl-1,2-diamine

Luciana I.N. Tomé, A.J. Lopes Jesus, R.A. Esteves de Castro,M. Helena S.F. Teixeira,João Canotilho, M. Ermelinda S. Eusébio

Journal of Chemical Thermodynamics 39 (2007) 1357–1362

Impact Factor: 1.939

http://dx.doi.org/10.1016/j.jct.2007.07.006

[5]

Conformational isomorphism of organic crystals. Racemic and homochiral atenolol
R. A. Esteves de Castro, João Canotilho, Rui M. Barbosa, M. Ramos Silva, A. Matos Beja, J. A. Paixão, J. Simões Redinha

Crystal Growth & Design 7 (2007) 496-500

Impact Factor: 4.215

http://dx.doi.org/10.1021/cg0601857

[4]

Infrared spectroscopy of racemic and enantiomeric forms of atenolol

R.A. Esteves de Castro, João Canotilho, Rui M. Barbosa, J. Simões Redinha

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 67 (2007) 1194-1200

Impact Factor: 1.511

http://dx.doi.org/10.1016/j.saa.2006.10.007

[3]

Novel organic hole transport layers for molecular electronic systems

H. D. Burrows, R. A. E. Castro, M. A. Esteves, B. Gigante, (the late) M. L. P. Leitão e A. C. Pauleta

Materials Science Forum 514-516 (2006) 8-12

Impact Factor: 0.399

http://dx.doi.org/10.4028/www.scientific.net/MSF.514-516.8

[2]

Infrared study of the acidic and basic forms of betaxolol

J. Canotilho, R. A. Esteves de Castro, M. H. S. F. Teixeira, M. Luísa P. Leitão, J. Simões Redinha

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 64 (2006) 279-286

Impact Factor: 1.511

http://dx.doi.org/10.1016/j.saa.2005.07.021

[1]

Phase transition of 1,2-cyclohexanediol isomers studied by polarised light microscopy and differential thermal analysis

M. Luísa P. Leitão, Ricardo A. E. Castro, Felisbela S. Costa, J. S. Redinha

Thermochimica Acta 378 (2001) 117-124

Impact Factor: 1.562

http://dx.doi.org/10.1016/S0040-6031(01)00590-1

NATIONAL PAPERS

[2]

Estudo de dois polimorfos da pirazinamida por calorimetria diferencial de varrimento e espectroscopia de infravermelho

Ricardo A. E. Castro, Teresa M. R. Maria, António O. L. Évora, João Canotilho, M. Ermelinda S. Eusébio

Boletim da Sociedade Portuguesa de Química 130 (2013) 53-58

https://www.spq.pt/magazines/BSPQuimica/661/article/30001860/pdf

[1]

Polimorfismo: Aspectos Científicos e Repercussão na Tecnologia Farmacêutica.

J. Simões Redinha, João Canotilho, Ricardo Castro e Sandra Nunes

Memórias da Academia das Ciências de Lisboa, Tomo XLIII (Volume I) 2011

Imprensa Nacional Casa da Moeda

ISBN: 9789722717014

https://www.incm.pt/portal/loja_detalhe.jsp?codigo=102096

PROCEEDINGS

Bioremediation Using Microalgae and Circular Economy Approach: A Case Study

Telma Encarnação , Artur Mateus, Florindo Gaspar, Anabela Massano, Sara Biscaia, Pedro Batalha Guincho, Bernardo A. Nogueira, Ricardo A. E. Castro, Tomás Archer de Carvalho, Maria Ermelinda S. Eusébio, Rui Fausto and Abílio J. F. N. Sobral

Materials Proceedings 8 (2022) 108

https://doi.org/10.3390/materproc2022008108

BOOK CHAPTER

Drug Nanocrystals

M. Ermelinda S. Eusébio, Ricardo A. E. Castro, Joäo Canotilho

In "Nanoparticles for Brain Drug Delivery" Edited By Carla Vitorino, Andreia Jorge, Alberto Pais, New York, Jenny Stanford Publishing 2021

http://dx.doi.org/10.1201/9781003119326-9

THESIS

[1]

Antagonistas Adrenérgicos Selectivos Beta 1: Estrutura do Atenolol

Tese de Doutoramento na especialidade de Química Farmacêutica apresentada à Faculdade de Farmácia da Universidade de Coimbra em 2007

https://estudogeral.sib.uc.pt/handle/10316/552

[2]

Estudos de Termomicroscopia e Calorimetria de Solução de Derivados Hidroxilados do Ciclo-Hexano
Tese de Mestrado em Química área de Química-Física apresentada no Departamento de Química da Universidade de Coimbra em 2000

UC.PT

Páginas pessoais

Ricardo António Esteves De Castro