RESEARCH SUMMARY

2007-TODAY

Participation in research projects

  • Chemistry Triggered by Infrared Vibrational Excitation: Developing a Powerful Tool for Highly-Selective Molecular Structure Manipulation (Researcher, Department of Chemistry, University of Coimbra, PTDC/QUI-QFI/28973/2017, 2019-present)
  • Novel Fused Ring Tetrapyrrolic Macrocycles as Highly Efficient Theranostic Agents for Cancer (Post-doc, Department of Chemistry, University of Coimbra, PTDC/QEQ-MED/0262/2014, 2016-2019) 
  • PhD in Organic Chemistry (Synthesis of pyrrolic compounds and their study against cancer: FCT SFRH/BD/61573/2009, 2009-2014)
  • Cancer Light Assisted Receding Oncology - (Development of new photosensitizers for PDT Researcher, Chymiotechnon, PRIME/CLARO/3/293, 2007)

Visiting researcher

  • Utrecht University, Department of Biology, Netherlands 11/2016 and 03/2018: Conjugation of photosensitizers with nanobodies for tumor-targeted photodynamic therapy
  • Trinity College Dublin, School of Chemistry, Ireland 09-12/2011: Synthesis of porphyrinic compounds for PDT of cancer

EDUCATION

  • PhD IN CHEMISTRY - SPECIALIZATION IN ORGANIC SYNTHESIS; 2014 University of Coimbra; Final classification: Approved with praise and distinction by unanimity
  • MSc IN CHEMISTRY (pre-Bologna) - SPECIALIZATION IN CHEMICAL PROCESSES; 2008 University of Coimbra; Final classification: Very Good
  • BSc IN INDUSTRIAL CHEMISTRY (pre-Bologna) - SPECIALIZATION IN QUALITY CONTROL; 2005 University of Coimbra; Final classification: 14 (0-20); Internship in AEMITEQ, Quality Control Laboratory, 2004-2005SCIENTIFIC AND TECHNICAL PRODUCTION

SCIENTIFIC AND TECHNICAL PRODUCTION

Selected Publications 

  • Nelson A. M. Pereira et al., Advances on photodynamic therapy of melanoma through novel ring-fused 5,15-diphenylchlorins, Eur. J. Med. Chem., v. 146, p. 395-408, 2018. 
  • Nelson A. M. Pereira et al., Platinum(II) Ring-Fused Chlorins as Near-Infrared Emitting Oxygen Sensors and Photodynamic Agents, ACS Medicinal Chemistry Letters, v. 8, p.310-315, 2017. 
  • Nelson A. M. Pereira et al., Novel 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridine Fused Chlorins as Very Active Photodynamic Agents for Melanoma Cells. Eur. J. Med. Chem., v. 103, p. 374-380, 2015. 

Patents

  • Ring-Fused Chlorins, Methods And Uses Thereof; Inventors: Hugh D. Burrows, Teresa M. V. D. Pinho E Melo, Arménio C. Serra, Nelson A. M. Pereira, Liliana Martelo, Marta Piñeiro, J. Seixas de Melo, João Pina, Maria F. Botelho, Ana M. Abrantes, Mafalda Laranjo; Internacional, WO2017145092, 2017.
  • Clorinas Fundidas de Platina(II), seus Métodos e Usos; Inventors: Hugh D. Burrows, Teresa M. V. D. Pinho E Melo, Arménio C. Serra, Nelson A. M. Pereira, Liliana Martelo, Marta Piñeiro, J. Seixas de Melo, João Pina, Maria F. Botelho, Ana M. Abrantes, Mafalda Laranjo; Portuguese, PT10918, 2017.
See all publications in my ORCID profile
 
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