Ivan Viegas
Email: iviegas@uc.pt | Twitter: @IvanViegasLab
ORCID | Google Scholar | ResearchGate | Web of Science | Scopus | LinkedIn | CiênciaVitae |
(last update 17-01-2023)
Latest News
- Featured on Aquafeed regarding Palma et al (2023)
- Featured as research highlight for FCTUC in October 2022: Video (PT only)
- Several features relative to Toomey et al. (2022):
- Front cover for Current Biology 32(19); Photo credits to PM Araújo;
- Editor pick (dispatch): Hill, GE (2022) Evolution: The biochemistry of honest sexual signaling. Current Biology 32(19) R1005 - R1007;
- Nature News and Views: Bray N (2022) On being and seeing red. Nature 609: 250.
- Our participation in 90 Seconds of Science for the Portuguese public radio broadcaster Antena1 (PT only).
- Check out our brand new logo for the ConTribuT Project!
- Some news on our recent publications from 2022a 2022b: press release / Público / MisPesces / Visão / As Beiras
Present Research Interests
- Aquaculture and fish metabolism: understanding of the metabolism of carnivorous fish important to Southern European aquaculture, such as gilthead seabream (S. aurata) and European seabass (D. labrax), and worldwide such as rainbow trout (O. mykiss), barramundi / Asian seabass (L. calcarifer) and Amazon tambaqui (Colossoma macropomum).
- Tracer studies in fish: keeping up with novel aquaculture feeds and developing experimental approaches to address the nutritional, enzymatic and hormonal regulation of intermediary metabolism using stable isotopes such as 2H and 13C and Nuclear Magnetic Resonance (NMR).
- NMR-based metabolomics in fish: develop tools for metabolomics in fish tissue and applications in the context of aquaculture.
- Comparative physiology and transversal approaches to metabolism - from fish to obesity and diabetes in mammals, fat accumulation in migrant birds, increase productivity in black soldier fly (Hermetia illucens), novel feed ingredients in weaned piglets.
>>>> See dedicated sections below <<<<
Recent publications (3)
Palma M, Magnoni LJ, Morais S & Viegas I (2023) Tributyrin supplementation in fish and crustacean nutrition: A review. Reviews in Aquaculture 15:785–800.
Martins et al. (2022) Impact of dietary Chlorella vulgaris and feed enzymes on health status, immune response and liver metabolites in weaned piglets. Scientific Reports 12: 16816
Toomey et al. (2022) A mechanism for red coloration in vertebrates. Current Biology 32: 4201-4214.e4212.
Utilization of glycerol as ingredient for fish feed - potential for aquaculture (mostly from PEIXEROL project [PTDC/CVT-NUT/2851/2014; funded by Fundação para a Ciência e a Tecnologia (FCT; Portugal) through national funds with co-funding from European Regional Development Fund (ERDF), within the Portugal 2020 Partnership Agreement, and COMPETE 2020]
Viegas et al. (2022a) On the Utilization of Dietary Glycerol in Carnivorous Fish - Part I: Insights Into Hepatic Carbohydrate Metabolism of Juvenile Rainbow Trout (Oncorhynchus mykiss) and European Seabass (Dicentrarchus labrax). Front Mar Sci 9: 836610.
Viegas et al. (2022b) On the Utilization of Dietary Glycerol in Carnivorous Fish—Part II: Insights Into Lipid Metabolism of Rainbow Trout (Oncorhynchus mykiss) and European Seabass (Dicentrarchus labrax). Front Mar Sci 9: 836612.
Tavares et al. (2022) Towards a semi-automated analysis of fish plasma by 1H NMR metabolomics - applications to aquaculture. Aquaculture 552: 738028.
Magnoni et al. (2021) Dietary glycerol inclusion decreases growth performance and nitrogen retention efficiency in rainbow trout (Oncorhynchus mykiss). Aquaculture: 736383.
Louvado et al. (2020) Effect of glycerol feed-supplementation on seabass metabolism and gut microbiota. Appl Microbiol Biotechnol 104: 8439-8453.
Panserat et al. (2020) Hepatic Glycerol Metabolism-Related Genes in Carnivorous Rainbow Trout (Oncorhynchus mykiss): Insights Into Molecular Characteristics, Ontogenesis, and Nutritional Regulation. Front Physiol 11:882.
Palma et al. (2019) Metabolic Effects of Dietary Glycerol Supplementation in Muscle and Liver of European Seabass and Rainbow Trout by 1H NMR Metabolomics. Metabolites 9: 202.
Rito et al. (2019) Utilization of glycerol for endogenous glucose and glycogen synthesis in seabass (Dicentrarchus labrax): A potential mechanism for sparing amino acid catabolism in carnivorous fish. Aquaculture 498: 488-495.
NMR-based metabolomics in fish
Tavares et al. (2022) Towards a semi-automated analysis of fish plasma by 1H NMR metabolomics - applications to aquaculture. Aquaculture 552: 738028.
Ferrari et al. (2022) Carbohydrate tolerance in Amazon tambaqui (Colossoma macropomum) revealed by NMR-metabolomics - Are glucose and fructose different sugars for fruit-eating fish? Comp Biochem Physiol D Genom Proteom 41: 100928.
Palma et al. (2021) Digesta and Plasma Metabolomics of Rainbow Trout Strains with Varied Tolerance of Plant-Based Diets Highlights Potential for Non-Lethal Assessments of Enteritis Development. Metabolites 11: 590.
Palma et al. (2020) Limitations to starch utilization in barramundi (Lates calcarifer) as revealed by NMR-based metabolomics. Front Physiol 11: 205.
Jarak et al. (2018) Response to dietary carbohydrates in European seabass (Dicentrarchus labrax) muscle tissue as revealed by NMR-based metabolomics. Metabolomics 14: 95. doi: https://doi.org/10.1007/s11306-018-1390-4
Utilization of dietary carbohydrates in carnivorous fish
Wade et al. (2020) Dietary starch promotes hepatic de novo lipogenesis in barramundi (Lates calcarifer). Brit J Nutr 124: 363-373.
Viegas et al. (2019) Impact of dietary starch on extrahepatic tissue lipid metabolism in farmed European (Dicentrarchus labrax) and Asian seabass (Lates calcarifer). Comp Biochem Physiol A Mol Integr Physiol 231: 170-176.
Silva-Marrero et al. (2019) The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of Sparus aurata. Biomolecules 9: 297.
Viegas et al. (2016) Effects of dietary carbohydrate on hepatic de novo lipogenesis in European seabass (Dicentrarchus labrax L.). J Lipid Res 57: 1264-1272.
Viegas et al. (2015) Contribution of dietary starch to hepatic and systemic carbohydrate fluxes in European seabass (Dicentrarchus labrax L.). Brit J Nutr 113: 1345-1354.
Metabolic adaptations to fasting and refeeding in carnivorous fish
Silva-Marrero et al. (2017) A transcriptomic approach to study the effect of long-term starvation and diet composition on the expression of mitochondrial oxidative phosphorylation genes in gilthead sea bream (Sparus aurata). BMC Genomics 18: 768.
Viegas et al. (2014) Expressional regulation of key hepatic enzymes of intermediary metabolism in European seabass (Dicentrarchus labrax) during food deprivation and refeeding. Comp Biochem Physiol A Mol Integr Physiol 174 38-44. doi:
Viegas et al. (2013) Effects of food-deprivation and refeeding on the regulation and sources of blood glucose appearance in European seabass (Dicentrarchus labrax L.). Comp Biochem Physiol A Mol Integr Physiol 166 399-405.
Viegas et al. (2012) Hepatic glycogen synthesis in farmed European seabass (Dicentrarchus labrax L.) is dominated by indirect pathway fluxes. Comp Biochem Physiol A Mol Integr Physiol 163 22-29.
Viegas et al. (2011) Analysis of glucose metabolism in farmed European sea bass (Dicentrarchus labrax L.) using deuterated water. Comp Biochem Physiol A Mol Integr Physiol 160: 341-347.
Development of NMR-based tools using stable isotopes
Coelho M, Mahar R, Belew GD, Torres A, Barosa C, Cabral F, Viegas I, Gastaldelli A, Mendes VM, Manadas B, Jones JG & Merritt ME (2023) Enrichment of hepatic glycogen and plasma glucose from H₂18O informs gluconeogenic and indirect pathway fluxes in naturally feeding mice. NMR in Biomedicine 36: e4837.
Viegas I, Di Nunzio G, Belew GD, Torres AN, Silva JG, Perpétuo L, Barosa C, Tavares LC & Jones JG (2022) Integration of Liver Glycogen and Triglyceride NMR Isotopomer Analyses Provides a Comprehensive Coverage of Hepatic Glucose and Fructose Metabolism. Metabolites 12: 1142.
Belew et al. (2019) Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis. J Lipid Res 60: 2050-2056.
Silva et al. (2019) Determining contributions of exogenous glucose and fructose to de novo fatty acid and glycerol synthesis in liver and adipose tissue. Metabol Eng 56: 69-76.
Rito et al. (2018) Disposition of a Glucose Load into Hepatic Glycogen by Direct and Indirect Pathways in Juvenile Seabass and Seabream. Scientific Reports 8: 464.
Marques et al. (2016) Determination of muscle protein synthesis rates in fish using 2H2O and 2H NMR analysis of alanine. Anal Biochem 509: 111-114.
Viegas et al. (2011) Analysis of glucose metabolism in farmed European sea bass (Dicentrarchus labrax L.) using deuterated water. Comp Biochem Physiol A Mol Integr Physiol 160: 341-347.
Metabolic adaptations of long-distance migrant birds
Lee M, Viegas I, Norte AC, Ramos JA & Araújo PM (2023) Assessing the fatty acid profile of migratory birds with different fuelling strategies. Ibis 165: 297-304
Toomey et al. (2022) A mechanism for red coloration in vertebrates. Current Biology 32: 4201-4214.e4212.
Araújo et al. (2022) Blood Metabolites and Profiling Stored Adipose Tissue Reveal the Differential Migratory Strategies of Eurasian Reed and Sedge Warblers. Birds 3: 359-373.
Araújo et al. (2019) Understanding how birds rebuild fat stores during migration: insights from an experimental study. Sci Rep 9: 10065.
Viegas et al. (2017) Metabolic plasticity for subcutaneous fat accumulation in a long-distance migratory bird traced by 2H2O. J Exp Biol 220: 1072-1078.
Studies of diabetes and obesity in mammalian models
Amorim et al. (2022) Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems. Redox Biology 55: 102400.
Flachs et al. (2017) Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype. Int J Obes 41: 372-380.
Varghese et al. (2016) Mechanisms Underlying the Pathogenesis of Isolated Impaired Glucose Tolerance in Humans. J Clin Endocrinol Metab 101: 4816-4824.
Varghese et al. (2016) Diabetes-Associated Variation in TCF7L2 Is Not Associated With Hepatic or Extrahepatic Insulin Resistance. Diabetes 65: 887-892.
Soares et al. (2012) Restoration of direct pathway glycogen synthesis flux in the STZ-diabetes rat model by insulin administration. Am J Physiol - Endocrinol Metab 303: E875-E885.
Book Chapters
Encyclopedia of the United Nations Sustainable Development Goals - Life Below Water, Leal Filho W, Azul AM, Brandli L, Lange Salvia A, Wall T (eds). Springer International Publishing:
- Palma M & Viegas I (2020) Aquaculture: Farming Our Food in Water.
- Rito J & Viegas I (2020) Fish Farming.
Viegas I, Carvalho RA, Pardal MA and Jones JG (2012). Advances and Applications of Tracer Measurements of Carbohydrate Metabolism in Fish. In Türker H (Ed.) New Advances and Contributions to Fish Biology, ISBN: 978-953-51-0909-9, InTech. DOI: 10.5772/54053
News & Event archive
La Vanguardia (SP; 2016)
ASBMB Today (Página 14; EN; 2016)
Antena 2 Ciência (Interview - 09:14; 2016)
TecnoAlimentar (PT; 2017)
MisPesces (SP; 2019)
Fish Metabolism - applications to aquaculture (Course - 8h; 2019)
CSIRO Aquaculture (EN; 2020)
MisPesces (SP; 2020)
MisPesces (SP; 2021)
