Methods to Sinthetize Scientific Evidence

Recommended Prerequisites

Recommended prerequesites.

Teaching Methods

Face to face theoretical presentation followed by examples e practical exercises.

Learning Outcomes

To organize epidemiologic, clincal and therapeutic information accordind to levels of scientific evidence in order tosupport de demonstration of the existance of added therapeutic value of the technology under analysis versuscomparators.

Work Placement(s)

No

Syllabus

Quantitative and quantitative methods of scientific evidence synthesis. Lietrature search. Systematic review.Conventional meta-analysis. Direct and indirect comparisons. Network meta-análises. Objective metrics forbenefiti/risk rations evaluation. Guidelines to conduct and report systematic reviews and meta-analysis.

Head Lecturer(s)

Carlos Miguel Costa Alves

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook forSystematic Reviews of Interventions version 6.2 (updated February 2021). Cochrane, 2021. Available fromwww.training.cochrane.org/handbook.
Berlin, J.A., Crowe, B.J., Xia, H.A. and Evans, S.J. (2019). The Use of Metaanalysis in Pharmacoepidemiology. InPharmacoepidemiology (eds B.L. Strom, S.E. Kimmel and S. Hennessy).
Dias S, Ades AE, Welton NJ, et al. Network metaanalysis for decision making: Wiley, 2018.
Mendes D, Alves C, Batel-Marques F. Number needed to treat (NNT) in clinical literature: an appraisal. BMC Med. 2017Jun 1;15(1):112. doi: 10.1186/s12916-017-0875-8.