Biosensors

Recommended Prerequisites

Knowledge of Analytical Chemistry, Organic Chemistry, Biochemistry.

Teaching Methods

Theoretical classes.

Laboratory work and small experimental projects related to the lectured topics.

Learning Outcomes

Development of biosensor devices for identification of specific compounds in important areas as health, environment, food industry and others.

To know the features of the main physiological and environmental transducers and their applications

To know the methods for detection, measurement and recording of biomedical signals.

To know the methods for biomedical signal analysis.

To identify the main nanomaterials employed in biosensors.

To know the preparation methods of the main nanomaterials.

To recognize the main application areas in biomedicine.

Work Placement(s)

No

Syllabus

I. Biosensor BASIC CONCEPT - Components and requirements. Inspiration from nature. Selectivity, sensitivity, stability and response time. Detection by biocatalytic or binding event. Enzymatic biosensors and immunosensors.

II. APPLICATIONS of biosensors in health, in process control, in the military area, and in the environment.

III. RECOGNITION ELEMENTS - Kind and immobilization. Concept, methods and (dis)advantages. Dependence from the receptor surface.

4. RECEPTOR SURFACES - Characterization and modification. Coating with sensory membranes.

V. IDENTIFICATION OF NANOMATERIALS in biosensors - Main nanomaterials. Molecular imprint polymers. Carbon materials (derived from graphite). Inclusion in composites.

VI. PREPARATION METHODS OF NANOMATERIALS - Radical polymerization. Graphene production by exfoliation and its modification.

Laboratory work in i) modification and ii) chemistry of materials and surfaces, applied to biosensors.

Head Lecturer(s)

Maria Goreti Ferreira Sales

Assessment Methods

Assessment
Laboratory work or Field work: 40.0%
Exam: 60.0%

Bibliography

Biosensors: Fundamentals and Applications, BD Malhotra, CM Pandey, 2^nd edition, Kindle Edition, 2019.

Biosensors: An Introductory Textbook. J Narang, CS Pundir, Pan Stanford Publishing, Taylor & Francis, 2017.

Biosensors: Essentials, G Evtugyn, Springer, 2014.

Principles of Chemical Sensors, Ed. Jirí Janata, 2^nd edition, Springer, 2009.

Chemical Sensors, An Introduction for Scientists and Engineers, Ed. Peter Gründler, Springer, 2007.

Artigos científicos recentes relacionados com os temas leccionados/Recent scientific papers related to the lectured topics.