Identification and Analysis of Organic Compounds
1
2023-2024
02005732
Chemistry
Portuguese
Face-to-face
SEMESTRIAL
5.0
Compulsory
2nd Cycle Studies - Mestrado
Recommended Prerequisites
Basic knowledge of spectroscopy and organic chemistry.
Teaching Methods
The teacher should present topics with updated information based on his experience as a researcher. Some scientific studies developed by the teacher can be discussed when they fall in the syllabus content. A topic will be given to be presented with an oral discussion. In this way the student will be followed more closely. A theme within the subject content of the curricular unit will also be presented on which the student must submit a written review.
Learning Outcomes
Knowledge and ability to understand
- Recognize and apply basic concepts and principles which allow the interpretation of spectra of organic compounds.
- Ability to analyze, synthesize and understand.
Applying knowledge and understanding
- Learn to apply acquired knowledge in the individual´s vocational area at the professional approach level.
Judgment / decision making
- Learn to substantiate arguments when making decisions
Communication
- Understand and know how to use information sources. Ability to search and use bibliography
- Acquire skills for communicating information clearly, with speech and other appropriate means.
- Acquire skills in structured presentations of scientific matters to a competent audience, ability to debate, whether orally or in writing.
Skills related to self-learning
- Have skills which enable self-learning throughout life.
Work Placement(s)
NoSyllabus
Nuclear Magnetic Resonance Spectroscopy
Perturbation of the total magnetization vector. Relaxation times
Chemical Shift
Chemical shift for protons and carbon thirteen
Anisotropic effects
Shift Reagents
Nuclear Spin Coupling
Proton coupling; Factors affecting the value of J
Deviations from the 1st order model
AB, ABX, ABMX and AA'BB' Systems
Spin Decoupling
Solvent Anisotropy Effect
Coupling with 13C
Nuclear Overhauser Effect
Molecular Movements
Intramolecular and Intermolecular Chemical Processes
Experiments Using Multiple Pulses
APT - Attached Proton Test
Polarization Transfer Methods: INEPT, DEPT
Measuring relaxation times
Bidimensional Spectra
COSY, INADEQUATE, HETCOR, HMQC, HSQC, HMBC, NOESY
Fundamentals of mass spectrometry
Ion Production: Chemical ionization, electron impact, FAB, electrospray
Detection and Analysis of Ions: abundance, fragmentation
Hyphenated techniques: GC-MS and LC-MS
UV / Visible and Infrared spectroscopies.
Head Lecturer(s)
Teresa Margarida Vasconcelos Dias de Pinho e Melo
Assessment Methods
Assessment
Synthesis work: 25.0%
Exam: 75.0%
Bibliography
“Spectrometric Identification of Organic Compounds”, R. M. Silverstein, F. X. Webster, D. J. Kiemle, John Wiley & Sons, Inc., 2005.
"Spectroscopic Methods in Organic Chenistry", Dudley H. Williams e Ian Fleming, McGraw-Hill Book Company, London, 1989.
"Spectroscopic Methods in Organic Chemistry", M. Hesse, H. Meier, B. Zeeh, Georg Thieme Verlag Stuttgart, 1997.
“Espectroscopia de Ressonância Magnética Nuclear”, António M. D'A. Rocha Gonsalves, Teresa M- V. D. Pinho e Melo, Imprensa da Universidade de Coimbra, 2007
"Espectroscopia Electrónica e Vibracional", António M. d’A. Rocha Gonsalves, M. Elisa da Silva Serra, Marta Piñeiro, Imprensa da Universidade, Coimbra, 2005.