Biosensors and Biomedical Signals

Academic year
Subject Area
Biomedical Engineering
Language of Instruction
Other Languages of Instruction
Mode of Delivery
ECTS Credits
2nd Cycle Studies - Mestrado

Recommended Prerequisites

Knowledge of Physics I and II, Analytical Chemistry, Organic Chemistry, Biochemistry Bioelectricity and Biomagnetism, Analysis and Processing of Biosignals, Electronics, Instrumentation and Data Acquisition Systems at the level of 1st cycle of studies.

Teaching Methods

Theoretical/Practical classes.

Seminars (mandatory).

Laboratory work and small experimental projects related to the lectured subjects.

Learning Outcomes

Development of biosensor devices for identification of specific compounds in important areas as health, environment, food industry and others.

To know the features of the main physiological and environmental transducers and their applications

To know the methods for detection, measurement and recording of biomedical signals.

To know themethods for biomedical signal analysis.

To know the main application areas in biomedicine.

Work Placement(s)



The concept of Biosensor. Selectivity, sensitivity, stability and response time. Detection by biocatalytic or by binding event. Enzymatic biosensors and imunossensores.

Biosensors applications.

Biological recognition elements. Immobilization of biological compounds.

Surface characterization and modification. Coatings with membrane sensors.

Transducers. Performance factors. In vitro and in vivo monitoring. Lab-on-a-chip

Biosensors stability. The evolution of the glucose biosensor. Last generation biosensors. Future prospects.

Physiological and environmental Transducers/Sensors. Principles and general concepts. Static and dynamic parameters.

Study and application of some sensors.

Readout, conditioning and amplifier electrical circuits.

Biomedical signals. Electrocardiography, Electromiography. Interference and noise.  Analog filters.

Analog and digital signals. Digitization. Sampling.  Quantization and aliasing errors.

Head Lecturer(s)

António Miguel Lino Santos Morgado

Assessment Methods

Report of a seminar or field trip: 15.0%
Synthesis work: 15.0%
Laboratory work or Field work: 20.0%
Exam: 50.0%


Biosensors, E.Hall

Medical Instrumentation: Application and Design, 3rd Edition, John G. Webster (Editor) ISBN: 0-471-15368-0 Hardcover 720 pages August 1997

The Measurement, Instrumentation and Sensors Handbook, edited by John G. Webster, CRC Press,1999

The Biomedical engineering Handbook, Ed. Joseph Bronzino, CRC Press, 2000

Sensors and Tranducers A Guide for technicians, 2nd ed. Ian Sinclair, 1998

Biomedical Signal Processing and Signal Modeling, Eugene N. Bruce, Wiley, 2001

Sensors and Signal Conditioning, R. Pallás-Areny/John Webster, John Wiley and Sons, 1991

Artigos científicos recentes relacionados com os temas leccionados/ Recent scientific papers related to the lectured subjects