Alzheimer's Disease and other Dementias, Cerebrovascular Disorders and Epilepsy
1
2023-2024
02038192
Neuroscience
English
Face-to-face
SEMESTRIAL
6.0
Compulsory
2nd Cycle Studies - Mestrado
Recommended Prerequisites
Not applicable.
Teaching Methods
Tutorial/Face to face; discussion of clinical cases; paper presentation and discussion.
Learning Outcomes
Dementias:
- Recognizing the epidemiological impact of dementia and Alzheimer's disease (AD)
- Clinical characterization, biomarkers-based diagnosis, genetics and innovative therapies of AD
- To describe the main mechanisms of neurodegeneration of amyloidosis, including prion diseases and transthyretin familial amyloid polyneuropathy (TFAP)
Cerebrovascular diseases:
- Recognising the national and international epidemiological relevance of Stroke
- Identification and characterization, classification and treatment of stroke
- Describing the main mechanisms of ischaemic stroke and new areas of investigation: Small vessels disease
Epilepsy:
- Recognizing the epidemiology of epilepsy according to the main risk groups
- Identification and treatment of the main ype of seizures and epilepsies
- New áreas of investigation: EEG, imaging and translational medicine.
Work Placement(s)
NoSyllabus
Dementia:
- The epidemiological features of dementia and AD
- A new concept of AD as a biological entity
- Clinical characterization, biomarkers-based diagnosis, genetics and innovative therapies in AD
- The main mechanisms of neurodegeneration of amyloidosis
- New classification systems of amyloidosis (prion diseases and TFAP)
Cerebrovascular diseases:
- National and international epidemiological relevance of stroke
- Classification and treatment of stroke
- Physiopathology and mechanisms of ischaemic stroke
- New areas of investigation: small vessels disease
Epilepsy:
- Epidemiology of epilepsy according to the main risk groups
- Classification of seizures, syndromes and epilepsies
- Characterization of the epileptic focus and mechanisms
- Ancillary tools of diagnosis and treatments (children and adults)
- New areas of investigation: EEG, imaging, genetics, neuropathology and tranlational medicine.
Head Lecturer(s)
Maria Isabel Jacinto Santana
Assessment Methods
Assessment
Exam: 100.0%
Bibliography
- Santana, I.et al. (2015). Acta Médica Portuguesa, 28(2), 182-188
- Baldeiras I, et al. (2012) Sinapse, 12(2): 14-22
- Lleo A, et al.(2015) Nat Rev Neurol, 11(1): 41-55
- Baldeiras I, et al (2009) J Neurol. 2009.256(9): 1540-50
- Adams D, et al. (2016) Curr Opin Neurol. 2016 Feb;29 Suppl 1:S14-26.
- Correia M, et al.(2017) Int J Stroke, 12(2):169-
- De Guio F, et al. (2014) Stroke, ;45(7):2124-2126
- Santo GC, et al. (2002) Cerebrovasc Dis 2002;13:Suppl 3:50-50
- Téllez-Zenteno, et al. (2012). Epilepsy Research and Treatment.
- Fisher, R et al. (2017). Operational classification of seizure types by the International League against Epilepsy: Position Paper of the ILAE Commission for the Classification and Terminology 58(4), 522-530.