Alzheimer's Disease and other Dementias, Cerebrovascular Disorders and Epilepsy

Year
1
Academic year
2023-2024
Code
02038192
Subject Area
Neuroscience
Language of Instruction
English
Mode of Delivery
Face-to-face
Duration
SEMESTRIAL
ECTS Credits
6.0
Type
Compulsory
Level
2nd Cycle Studies - Mestrado

Recommended Prerequisites

Not applicable.

Teaching Methods

Tutorial/Face to face; discussion of clinical cases; paper presentation and discussion.

Learning Outcomes

Dementias:

- Recognizing the epidemiological impact of dementia and Alzheimer's disease (AD)

- Clinical characterization, biomarkers-based diagnosis, genetics and innovative therapies of AD

- To describe the main mechanisms of neurodegeneration of amyloidosis, including prion diseases and transthyretin familial amyloid polyneuropathy (TFAP)

 

Cerebrovascular diseases:

- Recognising the national and international epidemiological relevance of Stroke

- Identification and characterization, classification and treatment of stroke

- Describing the main mechanisms of ischaemic stroke and new areas of investigation: Small vessels disease

 

Epilepsy:

- Recognizing the epidemiology of epilepsy according to the main risk groups

- Identification and treatment of the main ype of seizures and epilepsies

- New áreas of investigation: EEG, imaging and translational medicine.

Work Placement(s)

No

Syllabus

Dementia:

- The epidemiological features of dementia and AD

- A new concept of AD as a biological entity

- Clinical characterization, biomarkers-based diagnosis, genetics and innovative therapies in AD

- The main mechanisms of neurodegeneration of amyloidosis

- New classification systems of amyloidosis (prion diseases and TFAP)

 

Cerebrovascular diseases:

- National and international epidemiological relevance of stroke

- Classification and treatment of stroke

- Physiopathology and mechanisms of ischaemic stroke

- New areas of investigation: small vessels disease

 

Epilepsy:

- Epidemiology of epilepsy according to the main risk groups

- Classification of seizures, syndromes and epilepsies

- Characterization of the epileptic focus and mechanisms

- Ancillary tools of diagnosis and treatments (children and adults)

- New areas of investigation: EEG, imaging, genetics, neuropathology and tranlational medicine.

Head Lecturer(s)

Maria Isabel Jacinto Santana

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

- Santana, I.et al. (2015). Acta Médica Portuguesa, 28(2), 182-188

- Baldeiras I, et al. (2012) Sinapse, 12(2): 14-22

- Lleo A, et al.(2015) Nat Rev Neurol, 11(1): 41-55

- Baldeiras I, et al (2009) J Neurol. 2009.256(9): 1540-50

- Adams D, et al. (2016) Curr Opin Neurol. 2016 Feb;29 Suppl 1:S14-26.

- Correia M, et al.(2017) Int J Stroke, 12(2):169-

- De Guio F, et al. (2014) Stroke, ;45(7):2124-2126

- Santo GC, et al. (2002) Cerebrovasc Dis 2002;13:Suppl 3:50-50

- Téllez-Zenteno, et al. (2012). Epilepsy Research and Treatment.

- Fisher, R et al. (2017). Operational classification of seizure types by the International League against Epilepsy: Position Paper of the ILAE Commission for the Classification and Terminology 58(4), 522-530.