Clinical Virology

Recommended Prerequisites

The recommended prerequisites for the student to successfully achieve the objectives proposed in this course unit are knowledge in biology, molecular biology, microbiology and immunology.

Teaching Methods

The teaching of the course of Virology is based on theoretical classes of frequency not obligatory and practical classes of obligatory attendance. During the class are asked questions in order to stimulate student participation and assess the seizure affairs lected.

In practical classes are covered various aspects of the techniques available for the laboratory diagnosis of viral infections and demonstration classes are conducted in laboratorial context. Analysis and discussion of results of clinical cases are proposed in order to promote greater interconnection with reality.

Learning Outcomes

The unit of Virology aims to provide students with knowledge about the general characteristics of the main viruses responsible for human infections, clinical manifestations, diagnostic methods and treatment used.

The knowledge gained will enable students to understand the pathogenesis and clinical features of viral infections, as well as acquire skills in the area of viral diagnosis. The acquisition of this knowledge will be fundamental to the future performance of pharmacist as a health professional.

Work Placement(s)

No

Syllabus

Viral structure

Taxonomy of viruses

Viral replication

Pathogenesis of viral infections

Laboratory diagnosis of viral infections

Antiviral therapy

Herpesviridae family: HSV, VZV, HCMV, EBV, HHV-6, HHV-7, HHV-8

Retroviridae family: HIV-1, HIV-2, HTLV-I and HTLV-II

Papillomaviridae family: human papillomaviruses

Viral hepatitis: the hepatitis A virus, hepatitis E virus, hepatitis B virus, hepatitis D virus, hepatitis C virus, and

viruses G and TT

Parvoviridae family: parvovirus B19

Viruses associated with respiratory tract infections

Orthomyxoviridae family: influenza virus (A, B, C)

Coronaviruses and respiratory adenoviruses

SARS-CoV-2 and COVID-19

Viruses associated with acute gastroenteritis:

Rotaviruses

Caliciviruses

Astroviruses

“Enteric” adenoviruses

Head Lecturer(s)

Paula Cristina Santos Luxo Maia

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

Microbiologia Médica volume 2

Helena Barroso, António Meliço- Sivestre, Nuno Taveira (2014) Lidel.

Human Virology

Collier, L. and Oxford J. (Ed.) (2000) Oxford University press

Basic Virology

Wagner E. K. and Hewlett, M. J. (Ed.) (2004) Blackwell Publishing

Clinical Virology

Richman D. D., Whitley R. J. and Mayden F. G. (Ed.) (2002) ASM press, Washington, D.C.

Essentials of Diagnostic Virology

Storch G. A. (Ed.) (2000) Churchil Livingstone, New York.

Medical Microbiology

Murray P. R., Rosenthal, K. S. , Kobayashi, G. S., Pfaller, M. A. (2005) Ed. Michael Brown, Mosby Inc