Clinical Virology
1
2018-2019
02035810
Science and Health Technologies
Portuguese
Face-to-face
SEMESTRIAL
5.0
Compulsory
2nd Cycle Studies - Mestrado
Recommended Prerequisites
Knowledge in biology, molecular biology, microbiology and immunology is recommended to successfully achieve the objectives proposed in this course.
Teaching Methods
The Virology curriculum unit teaching will be based on non mandatory theoretical classes and mandatory laboratory classes.
The lectures are based on the classical model of imparting knowledge, supported with illustrative presentations of the subjects covered, using available audiovisual equipment. Some practical classes will be demonstrative classes conducted in laboratorial context, with realization of several techniques used in diagnosis of viral infections.
Learning Outcomes
The unit of Clinical Virology aims to provide students with knowledge about:
- The general characteristics of the main viruses responsible for human infections;
- The principal clinical manifestations, diagnostic methods and treatment used in human viral infections.
By this manner, it is expected that at the final of this curricular unit, the knowledge gained will enable students to:
- Identify and characterize the principal human viruses;
- Understand the pathogenesis and clinical features of viral infections;
- Identify the advisable laboratorial methods for the diagnostic of different human viral infections, as well as interpret the obtained results.
The acquisition of this knowledge will be fundamental to the future performance of the health professional.
Work Placement(s)
NoSyllabus
THEORETICAL EDUCATION
Viral structure
Taxonomy of viruses
Viral replication
Pathogenesis of viral infections
Antiviral therapy
Herpesviridae family: HSV, VZV, HCMV, EBV, HHV-6, HHV-7, HHV-8
Retroviridae family: HIV-1, HIV-2, HTLV-I and HTLV-II
Papillomaviridae family: human papillomaviruses
Viral hepatitis: the hepatitis A virus, hepatitis E virus, hepatitis B virus, hepatitis D virus, hepatitis C virus, and viruses G and TT
Family Parvoviridae: B19
Viruses associated with respiratory tract infections: influenza virus (A, B, C), rhinoviruses, coronaviruses, and respiratory adenoviruses
Viruses associated with acute gastroenteritis: rotaviruses, caliciviruses, astroviruses, and “enteric” adenoviruses
THEORETICAL-PRACTICAL
Laboratory diagnosis of viral infections
Detection of the viral particle
Detection of viral components: viral antigens and viral genome
Detection of viral antibodies
Diagnosis of infections by human herpesvirus, human immunodeficiency virus and hepatitis viruses
Head Lecturer(s)
Ana Miguel Duarte Matos Silva
Assessment Methods
Final assessment
Exam: 100.0%
Bibliography
Microbiologia Médica volume 2
Helena Barroso, António Meliço-Silvestre, Nuno Taveira (2014) Lidel.
Medical Microbiology
Murray P.R., Rosenthal, K.S., Kobayashi, G.S., Pfaller, M.A. (2013) Ed. Michael Brown, Mosby Inc
Human Virology
Collier, L. and Oxford J. (Ed.) (2011) Oxford University press
Basic Virology
Wagner E. K. and Hewlett, M. J. (Ed.) (2004) Blackwell Publishing
Clinical Virology
Richman D. D., Whitley R. J. and Mayden F. G. (Ed.) (2002) ASM press, Washington, D.C.
Essentials of Diagnostic Virology
Storch G. A. (Ed.) (2000) Churchil Livingstone, New York.