Oncobiology

Recommended Prerequisites

Molecular Biology, Cellular Phisiology, Biochmistry.

Teaching Methods

Classical teaching class along the semester, by using adequate audiovisual equipment.

Hands on  of relevant experiments for better understanding of important themes developed in the teorethical classes.

Solving of problems aimed at anticipating oncological consequences based in early detection data.

Presentation and debate of oncogenic themes of recent publication. Monthly short testing about the subject. Final global exam to ease the perception of the way the oncological themes are related.

Learning Outcomes

This course aim is to allow students to know the oncogenic process, that results from the functional imbalance of the regulation mechanisms responsible for cell homeostasis.. As a consequence of said imbalance, resulting in uncontrollled cell proliferation that origins tumors, evolving gradually to malignancy, i,. e, cancer. Therefore, the general pathways of cell signalling that induce cell proliferation are made clear, as it is also made clear the celll cycle and its regulation. The molecular mechanisms of the oncogenic process and ways for its prevention and therapy are also made clear.

Work Placement(s)

No

Syllabus

Programme (Main points)

1. Introduction to Oncobiology

2. Signalling transduction pathways

3. Cell cycle and its regulation

4. Molecular Biology of the oncological process.

Assessment Methods

Assessment
Laboratory work or Field work: 5.0%
Resolution Problems: 5.0%
Mini Tests: 30.0%
Exam: 60.0%

Bibliography

. B. Alberts, D. Bray, J. Lewis, M. Raff, K. Roberts and J. D. Watson. (2002) Molecular Biology of the Cell. Garland Publishing, Inc.., New York.
. H. Lodish, D. Baltimore, A. Berk, S. L. Zipursky, P. Matsudaira and J. Darnell. (2003). Molecular Cell Biology.

. J. M. Bishop and R. A. Weinberg. (1997). Molecular Oncology. Scientific American, Inc.,New York.