Bioinformatics

Recommended Prerequisites

Molecular Biology, Genetics, Algae and Fungi.

Teaching Methods

All classes will be taught throughout the semester.

The theoretical and practical lessons will be taught with the use of computers (1 per 2 students) connected to the Internet:

1 - analysis of genomics and proteomics;

2 - integration and management database (MACOI), which must be submitted in writing and orally.

Tutorial support for answering questions and solving exercises. Support the preparation of the report and oral presentation of the project work.

Learning Outcomes

Taught to use the computer tools to solve biological problems, development of open source language programs, analysis of nucleotide or amino acid, with open source applications and also the use of different informatic tools for the construction of databases for biological cataloging. Apply the acquired theoretical and experimental knowledge to solving problems on specific biological area, using the respective informatic tools. Recognizing the potential of different experimental methodologies and learn to apply them effectively and objectively in different situations. Prepare, analyze and convey information clearly and coherently. Knowing which sources most suitable for research and resolve particular subject independently. 

Work Placement(s)

No

Syllabus

1 - Genomic and proteomic analysis module:

   a) Internet resources
   b) open source applications
   c) FASTA and Blast
   d) analysis of nucleotide sequences
   e) identification of genes
   f) Protein analysis.

2 - Phylogenetic analysis module

3 - Bibliographic databases, patents and biodiversity module:

   a) Bibliographic databases and citing references in scientific texts (Endnote Web program)
   b) International biodiversity databases projects;
   c) databases for patents.

4 - Geographic information systems module.

Assessment Methods

Assessment
Project: 50.0%
Resolution Problems: 50.0%

Bibliography

- Lesk AM (2005) Introduction to Bioinformatics, 2nd Edition. Oxford University Press. ISBN: 0199277877 (disponível na biblioteca Botânico). 

- Mount DW (2004) Bioinformatics: Sequence and Genome Analysis, 2nd Edition. Cold Spring Harbor Laboratory Press. ISBN: 0879697121 (disponível na biblioteca Botânico).

Recursos WEB:

BASES DE DADOS BIBLIOGRÁFICAS

http://isiknowledge.com/

http://www.endnoteweb.com/

http://scientific.thomsonwebplus.com/

https://estudogeral.sib.uc.pt:8443/dspace/

https://webvpn.uc.pt/webvpn.html

BASES DE DADOS PATENTES

http://www.uc.gats

http://pt.espacenet.com/

BASES DE DADOS BIOLÓGICAS

http://www.catalogueoflife.org/

http://www.gbif.org/

http://www.algaebase.org/

http://macoi.ci.uc.pt/