Fundamentals of Medicinal Chemistry
1
2018-2019
02031627
Medicinal Chemistry
Portuguese
English
Face-to-face
SEMESTRIAL
6.0
Elective
Non Degree Course
Recommended Prerequisites
Not applicable.
Teaching Methods
Expositive classes and seminars delivered by specialists with students interaction according to what is expected at the PhD level.
Learning Outcomes
Provides a common scientific background and key concepts in drug discovery to all graduate students.
Work Placement(s)
NoSyllabus
1. Administration, biodistribution and fundamental pharmacokinetics
2.Lead validation
3. Drug targets. enzymes, receptors, nucleic acids
4. The prodrug concept - application in drug design. Soft drugs. Drug targeting
5. Hit discovery strategies.
6. Chemical libraries
7. Bridging drug synthesis to biological testing
8. Targets for drug development in ageing and age-related neurodegenerative disorders
9. Metabolism
Head Lecturer(s)
Carlos Alberto Fontes Ribeiro
Assessment Methods
Assessment
Exam: 100.0%
Bibliography
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