Organic Chemistry II

Academic year
Subject Area
Área Científica do Menor
Language of Instruction
Mode of Delivery
ECTS Credits
1st Cycle Studies

Recommended Prerequisites

General Chemistry, Organic Chemistry  I.

Teaching Methods

Contact hours will be made up of classical theoretical lectures with fundamental topics in Organic Chemistry. The use of the blackboard will be preferred, favoring a more dynamic participation of the students. Audiovisual methods will be used to explore and complement concepts. The contact with students should promote self-learning which is guided through tutorial orientation.

Learning Outcomes

Knowledge and ability to understand

1.1. Recognize and apply basic concepts and principles in Organic Chemistry.

1.2. Ability to analyze, synthesize and understand.

Applying knowledge and understanding

2.1. Learn to apply acquired knowledge in the individual´s vocational area at the professional approach level.

Judgment / decision making

3.1. Ability to solve problems in Organic Chemistry.

3.2. Learn to substantiate arguments when making decisions


4.1. Understand and know how to use information sources. Ability to search and use bibliography

4.2. Acquire skills for communicating information clearly, with speech and other appropriate means. Acquire skills in structured presentations of scientific matters to a competent audience, ability to debate, whether orally or in writing.

Skills related to self-learning

5.1. Have skills which enable self-learning throughout life

Work Placement(s)



Aldehydes and Ketones: Nucleophilic Addition, Reaction with Amines, Grignard and organolithium reagents, Wittig reaction, Oxidation and Reduction, Aldol Condensation

Arenes and Aromaticity: Electrophilic Aromatic Substitution, Nucleophilic Aromatic Substitution, The Birch Reduction. Reactivity of Alkylbenzenes, Reactivity of Benzylic Halides

Carboxylic Acids and Derivatives: Synthesis of Esters, Acyl Chlorides, Acid Anhydrides and Amides. Hydrolysis, Reduction, Reaction with Grignard reagents. Decarboxylation of malonic acids. Synthesis and Reactivity of Nitriles. Hofmann Rearrangement. Acetoacetic synthesis

Amines: Basicity. Reactivity as nucleophiles,. Reductive Amination. Hofmann Elimination.  Nitrosation of Amines. Reactivity of Aryl Diazonium Salts. Azo Coupling.

Alcohols: Synthesis (from carbonyl compounds and epoxides) and Reactivity

Conjugation in Dienes and Allylic Systems

Retrosynthetic Analysis

Determining Organic Strutures: Mass, NMR (1H and 13C) and IR Spectroscopy

Head Lecturer(s)

Teresa Margarida Vasconcelos Dias de Pinho e Melo

Assessment Methods

Exam or Midterm.: 100.0%


1. Vollhardt, P. C.; Schore, N.E.; Organic Chemistry, W. H. Freeman and Company, New York.

2. Carey, F. A.; Organic Chemistry, McGraw-Hill, New York.

3. Clayden, J.; Greeves, N.; Warren, S.; Wothers, P.; Organic Chemistry, Oxford University Press, New York.