Mathematics I and 2; General Chemistry I and II; General Physics I and II; Physical Chemistry (Chemical Thermodynamics and Kinetics); Organic Chemistry I.
Face-to-face theoretical lectures and problem-solving sessions. Evaluation of skills acquired is done by a final written exam.
Understand and use chemistry concepts from other disciplines in the context of Biological Chemistry
Capacity to analyse information
Aplication of the know-how obtained on the resolution of problems in new situations
Ability to do experimental work in the laboratory and to interpret the data
Suport and argue oraly, and in writing, regarding decisions taken
Understand and know how to use sources of information namely bibliography search and use
Ability to express the knowhow gained, namely to non-specialists
Development of self learning competence.
1. Water: Physico-chemical properties and as a solvent
2. Saccharides: Structure and nomenclature, Stereochemistry, reactivity and properties as polymers
3. Proteins: Amino acids and their chemical properties; primary, secondary, tertiary and quaternary structure of proteins. Interaction with other molecules; cooperativity and allosterism
4. Lipids and Biological Membranes: Chemical structure and physico-chemical properties of lipids. Aggregation in water, polymorphism. The "Fluid Mosaic" model for biological membranes, permeation and transport
5. Nucleic Acids: Chemical constitution and structure. Physical properties: electrostatics; and rheology. Interactions with other molecules. The genetic code. General principles of replication, transcription and translation
6. Biological Catalysis: Overview of the general principles of chemical catalysis. Proteins as catalysts (enzymes) and the mechanisms of enzymatic catalysis. Enzyme kinetics, the Michaelis e Menten equation, inhibition.
Maria João Pedrosa Ferreira Moreno Silvestre
Livros de texto recomendados para o ano lectivo 2013/2014:
Donald Voet, and Judith G. Voet: BIOCHEMISTRY, John Wiley & Sons,4th Edition, 2011; ISBN-10: 0470570954
Jeremy Berg, John L. Tymoczko, and Lubert Stryer: BIOCHEMISTRY, W.H. Freeman & Company, 7th Edition, 2011, ISBN-10: 1429276355