Analytical Chemistry I

Recommended Prerequisites

General Chemistry I and II, Physical Chemistry I, Inorganic Chemistry, Chemistry Laboratorial Techniques, Chemistry Laboratory I.

Teaching Methods

The lectures are intended to build up solid chemistry foundations, which are used for understanding of different aspects of analytical chemistry. They are supported with audiovisual presentations. The TP classes will closely follow the lectures. The active involvement of the students in the discussion of the resolution of the problems will be asked. These questions will be provided at the beginning of the semester and are the subject of study prior to class.

Learning Outcomes

The curricular unit  aims to provide an overview of the role of analytical chemistry in science and society, providing introductory notions of statistical data analysis and of analytical methods validation, highlighting their importance in the quality of results, and to present and discuss the fundamental principles and applications of volumetric and gravimetric methos of analysis as well as of some thermal analysis and chromatographic methods.

Work Placement(s)

No

Syllabus

1 - Introduction: The objective of Analytical Chemistry. The role of analytical chemistry in science and society. Analytical process. Stages of the analytical process.

2 - Introduction to data processing in Analytical Chemistry: Types of errors in analytical chemistry. Accuracy and precision. Statistical treatment of experimental data: mean, standard deviation, confidence intervals and significance  tests, rejection of data. Calibration methods. Linear regression. Limits of detection and quantification. Uncertainty and its quantification.

3 - Introduction to the validation of analytical methods

4 - Volumetric and gravimetric methods of analysis. Acid-base, oxidation-reduction, complexation and precipitation volumetry. Gravimetric analysis.

5 - Thermal analysis. Differential thermal analysis and differential scanning calorimetry, thermogravimetry.

6 - Chromatography: gas chromatography, high performance liquid chromatography, supercritical fluid chromatography.

Head Lecturer(s)

Maria Ermelinda da Silva Eusébio

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

 -Fundamentos de Química Analítica, D. Skoog, D. M. West, F.  J. Holler, S. R. Crouch, Thomsom, S. Paulo, 2006.

 

- Princípios de Análise Instrumental, D. A. Skoog, F. J. Holler, T. A. Nieman,  Bookman, São Paulo, 2002.

 

-Quantitative Chemical Analysis, D.C. Harris, W. H. Freeman, New York, 2003.

 

- Analytical Chemistry, R. Kellner, J.-M. Mermet, M. Otto, H. M. Widmen, Wiley-VCH, Weinheim, 1998.

 

- Introduction to Thermal Analysis-Techniques and Applications, M. E. Brown, Kluwer Academic Publishers, Dordrecht, 2001.