Pharmacology I

Recommended Prerequisites

 All curricular units of the 1st and 2nd year.

Teaching Methods

There are theorical lessons in the classroom, and teaching  in groups, performing tasks or solving problems or cases.

Learning Outcomes

To characterize a drug, medicine or toxic. To know what is the R & D of a drug. Understanding the regulation system in Portugal and Europe. To know very well the ADME system (pharmacokinetics) and  how drugs act (pharmacodynamics) and how drugs are tested. To have notions of Evidence Based Medicine. To understand  interactions. To characterize and understand  neurotransmission and neuromodulation. To know the pharmacology of pain and pain control. To know drugs of abuse. Understanding what are biological medicines, generic drugs and biosimilars. Have notions of pharmacoeconomics.

Work Placement(s)

No

Syllabus

General concepts. OTC´s and prescription drugs. Generic drugs. Regulation of medicines. The basics of Pharmacoeconomics. Molecular Pharmacology. Evidence Based Medicine. Clinical trials and rational choice of a drug. Pharmacokinetics and pharmacodynamics. Interactions. Adverse reactions and toxic effects. Neurotransmission and neuromodulation. Drugs of the autonomic nervous system. Central and peripheral analgesics. Nonsteroidal antiinflammatory drugs and steroids drugs. Rheumatic disease modifying drugs (DMARD´s). Biological drugs. Local anesthetics. General anesthetics. Pre-anesthetic medication. General inhalation anesthetics, intravenous and  intramuscular anesthetics. Recovery room. Miorelaxants. Antihistamines H1 or H2. Treatment of somatic, visceral and neuropathic pain and headache Drugs of abuse.

Head Lecturer(s)

Frederico Guilherme Sousa Costa Pereira

Assessment Methods

Continuous assessment
Resolution Problems: 7.5%
Frequency: 92.5%

Final assessment
Resolution Problems: 7.5%
Exam: 92.5%

Bibliography

-Rang and Dale´s Pharmacology, Rang et  al. edts, Elsevier

-S Guimarães, Daniel Moura e Patrício Soares da Silva Coordenadores. Terapêutica Medicamentosa e Suas Bases Farmacológicas, 6ª ed., 2014 Porto Editora.

-Bertram G. Katzung, Basic & Clinical  Pharmacology, Int. Edition, McGraw Hill Companies.

-Goodman & Gilman, The Pharmacological Basis of Therapeutics, McGrawHill Companies.

-deVriesTPGM, TPGM, Henning DH,  Hogerzeil HV and  FresleD. Guide to Good Prescribing. OMS ,Genève , 1995

-Slides T and P