Immunology I

Year
2
Academic year
2022-2023
Code
01014234
Subject Area
Morphology, Structure and Function
Language of Instruction
Portuguese
Mode of Delivery
Face-to-face
Duration
SEMESTRIAL
ECTS Credits
2.5
Type
Compulsory
Level
1st Cycle Studies

Recommended Prerequisites

NA

Teaching Methods

Lectures: These classes aim to stimulate students to acquire core competencies and the ability to solve problems and self-learning.

Practical Laboratorial: These classes aim to provide the knowledge and understanding in laboratory terms of the Immune System to develop and apply in practical cases .

Learning Outcomes

- Define and describe the principle features associated with the structure, development and function of the immune system

- Define the physical, cellular and molecular processes associated with the immune response.

- Define the key mechanisms used by the immune system as protection against pathogens.

- Define the key mechanisms of immunological ageing and immunoendocrine and neuroimmune crosstalk.

- Demonstrate an understanding of key concepts in immunology concerning cell differentiation, activation and regulation.

- Collect, evaluate and integrate information drawn from a range of sources to generate written and oral outputs that highlight the importance of understanding the immune system.

Work Placement(s)

No

Syllabus

Biology and Physiology of the Immune System

-History of Immunology

-Phylogenetic evolution of immunoinflammatory response

-Characterization of the structural basis of the Immune System

-Innate and Acquired Immunity

-Cells and tissues of immune system

-Immunogenetics

-Antigens, antibodies and cell receptors

-Antigen-antibody reaction

Cytokines

-Complement Activation

-Mechanisms of Cytotoxicity

-Cellular Conditioning - Th1/Th2/Th17 responses

-Mechanisms of regulation of the immune response

-Cell Activation

-Suppression and immune tolerance

-Immune Response to Biological Aggressors:

-Nutrition and immunoinflammatory System

-Immunoendocrinology

-Neuroimmunology

-Evolution of the immune system (from Child to the Elderly).

Head Lecturer(s)

Helena Manuel Pina Oliveira Sá

Assessment Methods

Assessment
Other: 5.0%
Resolution Problems: 5.0%
Synthesis work: 5.0%
Exam: 85.0%

Bibliography

-Cellular and Molecular Immunology, 8th Edition - Abbas & Lichtman & Pillai. 2014.

-Fundamentos de Imunologia (2ª Edição) - Fernando A. Arosa, Francisco C. Pacheco, Elsa M. Cardoso - Editor: Lidel.2012.

-Kuby Immunology (7ª Edição) - Judy Owen, Jenni Punt, Sharon Stranford. 2012.

-Janeway’s Immunobiology 8 with Case Studies in Immunology 6 - Kenneth Murphy, Raif Geha, Luigi Notarangelo. 2011.

-Roitt's Essential Immunology - Peter J. Delves, Seamus J. Martin, Dennis R. Burton, Ivan M. Roitt. 2011.

-Artigos seleccionados de revistas científicas (Trends in Immunology, Nature Immunology, Current Opinion in Immunology, etc.)