Advanced Concepts in Cardiovascular Sciences

Recommended Prerequisites

Not applicable.

Teaching Methods

a) Conferences/ talks concerning specific themes

b) Seminaries/ round tables concerning emerging and controversial themes in the cardiovascular field

c) Individual and group work with the objective of promoting the scientific method in raising research hypotheses

The evaluation will include:

a) Presentation of a research article concerning a specific theme of the course.

b) Presentation and discussion of a proposal for a potential research project.

c) Multiple choice test.

Learning Outcomes

One of the objectives of this curricular unit  is to provide students with the competences required to understand the importance of a transversal and multidisciplinary research process in the cardiovascular field, that integrates, in a coherent fashion, contents from basic research and translational/clinical research. With this it is intended that students have an integrated perspective of research in the cardiovascular field, from the molecular and cellular mechanisms involved in regulating cardiac function, as well as those related to physiopathological changes associated with cardiovascular disease. In this context, this course is intended to be multidisciplinary, where the student can integrate and relate concepts and knowledge stemming from emerging areas of cardiovascular research, including molecular and cellular biology, physiology, physiopathology, diagnostics and treatment.

Work Placement(s)

No

Syllabus

A. Molecular and Cellular biology in cardiovascular research

1. Mechanisms of protein quality control in cardiac cells - Proteostasis

2. miRNA: Transcriptional regulation of  cardiac homeostasis

3. Genomics of Cardiomyopathies

B. Cardiovascular Regenerative Medicine

1. the role of cardiac microenvironment in heart regeneration

2. repairing and regenerating heart tissue with cell therapy

C.  Cardiovascular imaging and diagnostics

D. Clinical cardiovascular epidemiology

E. Vascular Medicine

1. endothelial metabolic dysfunction

F. Cardiovascular Pharmacology

G. Computational  modeling of cardiovascular function.

Head Lecturer(s)

Lino Manuel Martins Gonçalves

Assessment Methods

Assessment
Exam: 20.0%
Frequency: 20.0%
Project: 60.0%

Bibliography

Artigos cientificos publicados em revistas internacioanis da especialidade com revisão por pares

 

Scientific papers published in international scientific  journals with peer-review