General and Inorganic Chemistry

Recommended Prerequisites

Chemistry – secondary education.

Teaching Methods

This course unit has a theoretical and a practical components.

Lectures are preferably expository. Moreover practical problems and case studies are proposed in order to ensure a proper understanding of the program. The students have access to support material and bibliography in order to be prepared to solve some applying exercises.

In practical classes are applied some of theoretical knowledge, transposing the study for a more practical aspect. Several experimental procedures will be studied. The student´s autonomy and the capacity for interpretation and discussion of results are stimulated. 

Learning Outcomes

At the end of the course of General and Inorganic Chemistry is intended that students are able to:

- Develop knowledge about atoms and their interactions,

- Understand the variation of the properties of the elements by their position in the periodic table,

- Identify different types of chemical reactions involved in experimental procedures,

- Know the biological activity of some elements (essential or trace) and how to control this activity,

- Realize nuclear transmutations that occur in some unstable elements and their biological importance,

- Develop preparation, quantification and purification analytical methodologies for some compounds with pharmaceutical importance.

Work Placement(s)

No

Syllabus

Lectures and practical classes

Introduction

Atoms, molecules and ions

Chemical formulas, nomenclature

Chemical bonds

Solutions

Study of the elements of the periodic table

hydrogen

representative elements

transition metals

Bioinorganic Chemistry

role of elements (essential and trace) in biological systems

transition metals and coordination chemistry

metal complexes in drug action and biological systems

chemotherapy with compounds of non-essential elements

Basics of Nuclear Chemistry

radioactive decay

production of radionuclides

applications of radionuclides

non pharmaceutical applications

radiopharmaceuticals

radiopharmaceuticals

Studying methods of preparing and analyzing compounds under pharmacopoeias guidelines

preparation and quantification of inorganic compounds

Examples and applications.

Green chemical processes.

Head Lecturer(s)

Alcino Jorge Lopes Leitão

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

Livros:
Chang, Raymond.;Química, 8ª Ed.; McGraw-Hill, 2005
Rayner-Canham, Geoff and Overton, Tina;Descriptive Inorganic Chemistry, 5th Ed.; Freeman, New York, 2010
Cavaleiro, A. M. V.;Química Inorgânica Básica, 2ª Ed.; Universidade de Aveiro, 1999
James C. Dabrowiak;Metals in Medicine; John Wiley & Sons, 2009
Nicholas P. Farrell;Uses of Inorganic Chemistry in Medicine; Royal Society of Chemistry, 1999
Wolfgang Kaim, Brigitte Schwederski;Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life; John
Wiley & Sons; 1994
Gopal B. Saha;Fundamentals of Nuclear Pharmacy; 5th Ed., Springer, 2004
Handbook of Radiopharmaceuticals, Radiochemistry and Applications; Ed. Welch, M. J. and Redvanly, C. S., Wiley,
2003
Daniel C. Harris;Quantitative Chemical Analysis; Freeman; 2010
Artigos:
Barry NPE, Sadler PJ;Chem. Commun.2013,49, 5106
Guo Z, Slader PJ;Angew. Chem. Int. Ed.1999,38, 1512
Web:
Tabela Periódica Interativa: http://acswebcontent.acs.org/games/pt.html