General Pharmacology
2
2018-2019
02020509
Pharmaceutical Sciences
Portuguese
Face-to-face
SEMESTRIAL
5.0
Compulsory
2nd Cycle Studies - Mestrado
Recommended Prerequisites
Cellular Biology, Molecular Biology; Histology and Human Embryology; Human Anatomy and Physiology.
Teaching Methods
The teaching methodologies used in this course include:
- Lectures
- Presentation and discussion of scientific papers
- Seminars
Final exam (75%)
Presentation and discussion of scientific papers (25%)
Learning Outcomes
Upon completion of this course unit, the student will be able to: i) Know and understand the general mechanisms of drug action; ii) Know and understand the mechanisms of absorption, distribution, metabolism and elimination of drugs; ii) understand the adverse reactions to drugs, drug interactions and toxicity of drugs; iii) To know the stages of drug development and evaluation of quality / safety / efficacy of medicines.
Work Placement(s)
NoSyllabus
Drug / medicine and dosage forms.
The mechanisms of drug action: general principles, cellular and molecular aspects.
The general cycle of drugs in the body: Absorption, Distribution, Metabolism and Elimination.
Changes in the response due to genetic problems. The Pharmacogenetics.
Adverse reactions to drugs.
Drug interactions.
Toxicity of drugs and the importance of Pharmacotoxicology.
Phases of drug discovery and development.
The steps for assessing quality / safety / efficacy of medicines.
Head Lecturer(s)
Cláudia Margarida Gonçalves Cavadas
Assessment Methods
Assessment
Research work: 25.0%
Exam: 75.0%
Bibliography
Rang, Dale, Ritter & Flower. Rang & Dale's, Pharmacology. Churchill Livingstone, Elsevier, 6th Edition, 2007. ISBN: 978-0-443-06911-6.
Brunton LL, Lazo JS, Parker KL (eds.). Goodman & Gilman’s The Pharmacological Basis of Therapeutics. McGraw‐Hill, 11th Edition, 2006. ISBN0-07-142280-3
Artigos científicos