Topics in Medicinal Organic Synthesis

Recommended Prerequisites

Two semesters of Organic Chemistry

Teaching Methods

The teacher will present material with updated information based on his research experience.

Some exercises, whose resolution should be done with an oral discussion, will be proposed. Thus, an escort will be provided closer to the student. It should also be offered an issue selected from the course contents and the student must submit an updated review work.

The student will fit an effort of self-learning, however, may be partially guided through a learning tutorial.

Work Placement(s)

No

Head Lecturer(s)

Teresa Margarida Vasconcelos Dias de Pinho e Melo

Assessment Methods

Assessment
Resolution Problems: 20.0%
Synthesis work: 30.0%
Frequency: 50.0%

Bibliography

Organic Chemistry, Clayden, Greeves, Warren, Wothers, Oxford University, 2001.
Guidebook to Organic Synthesis, R. K. Mackie, D. M. Smith, R. A. Aitken, 3rd Edition, 1999.
Heterocyclic Chemistry, T. L. Gilchrist, Longman Scientific & Technical, Third Edition, 1997.
Contemporary Drug Synthesis, J. J. Li, D. S. Johnson, D. R. Sliskovic, B. D. Roth, Wiley, 2004.
Strategies for Organic Drug Synthesis and Design, 2º Ed., Daniel Lednicer, Wiley, 2009.

The Organic Chemsitry of Drug Synthesis, D. Lednicer, Wiley, New Jersey, 2008.
Chirality in Industry. The commercial manufacture and applications of optically active compounds, A.N.Collins, G.N.Sheldrake, J. Crosby, Wiley, Chichester, 2nd Edition 1995.
Transition Metal Reagents and Catalysts. Innovations in Organic Synthesis, J. Tsuji, Wiley, Chichester, 2000.
Handbook of Green Chemsitry & Technology, J. Clark & D. Macquarrie, Blackwell Publishing, Oxford, 2002.
Transition Metal Complexes as Potential Therapeutic agents, S. Rafique, M. Idrees, A. Nasim, H. akbar, A. Athar, Biotech and Molec. Biol. Rev., 5, 2010, 38-45.