Organometallic Chemistry and Catalysis

Recommended Prerequisites

Introductory inorganic and organic chemistry knowledge; Good english level.

Teaching Methods

The course will encompass theoretical lectures, T, that will present relevant topics. Selected exercises , TP, will be discussed to apply knowledge in the classroom. Along the semester the student will choose a topic to make a written/oral presentation based on a real industrial example for implementation of a greener process.

Final seminar for presentation and discussion of the results obtained by the student in a small search developed during the semester.

Learning Outcomes

1. Understand basic concepts and principles of organometallic synthesis and reactivity

2. Ability to analyze, synthesize and understand processes involving organometallic synthesis and manipulation. 3. Understand  the application of acquired knowledge in their vocational area at the level of professional approach including the development and use of catalysts in industry.

4. Capability of resolution / decision in solving problems within the field of catalysis processes on a larger scale. 5. Understand  the use of data bases sources of information.and  enhance the capability to search and use bibliography

6. Acquire skills to decide the best strategy to make a chemical synthesis of an unknown compound using organometallics.

Work Placement(s)

No

Syllabus

1. Organoalkaline Reagents

Reagents for the synthesis of organomagnesian and organolithium compounds – synthesis and manipulation. Synthetic applications.

2.Bonds and reactions of transition metal complexes

Syntheses, structure and stability organometalic complexes: substitution reactions; oxidative addition; redutive elimination; insertion, isomerization and elimination  reactions.

3.Homogeneous and heterogeneous catalytic processes with industrial application

Principles of homogeneous and heterogeneous catalysis; fundamentals and industrial examples of hydroformylation and carbonylation reactions; catalysed polymerization reactions; Butter synthesis: heterogeneous hydrogenation reaction ;zeolites as heterogeneous acid catalysts.

4.Oxidação de olefinas

Ethylene oxidation to acetaldehyde: Wacker process

Exemples of catalytic process to promote epoxidation of olefins.

5-Biocatálise

Principles; Exemples of aplication of bio-processes  in industrial synthesis 

Head Lecturer(s)

Maria Miguéns Pereira

Assessment Methods

Assessment
Synthesis work: 10.0%
Mini Tests: 20.0%
Exam: 70.0%

Bibliography

1. Fundamentos Y Aplicaciones de la Catálisis Homogénea, L.A. Oro, E. Sola, Zaragoza, 2000.

2. Catalysis from Theory to Application. An Integrated Course. J. L. Figueiredo, M.M.Pereira, J. Faria, Universidade de Coimbra, Press, Coimbra , 2008.

3. Organometallic Chemistry and Catalysis, 2nd ed. Didier Astruc, Springer-Verlag Berlin Heidelberg 2007.

4. Industrial Catalysis: A Practical Approach, 2ª ed., Jens Hagen, John Wiley & Sons, Dordrecht, 2006.

5. Homogeneous Catalysis. Understanding the Art. P. W. N. M., van Leeuen, John Wiley & Sons, Dordrecht, 2004.

6. Organometallics in Synthesis M. Schlosser ed., Jonhn Willey & Sons, Chichester, 1997.

7. Zeólitos. Um Nanomundo ao Serviço da Catálise. M. Guisnet, F. Ramôa Ribeiro, Fundação Calouste Gulbenkian, Lisboa, 2004.8 Organometallic Reagents in Synthesis”, P.R. Jenkins, Oxford Sci. Pub., Oxford, 1992.

9. Química Síntese e Estrutura. Uma Abordagem Prática” H.D.Burrows, Mariette M. Pereira, Escolar Editora, Lisboa 200.