Anatomy and Fisiology of the Pro and Antinociceptive System

Recommended Prerequisites

Not applicable.

Teaching Methods

Lectures.

Writing assessment test: 100%.

Learning Outcomes

To know peripheral mechanisms of pain.
To know the peripheral structure and anatomical organization of cutaneous and deep primary afferents.
To know the peripheral molecular and biochemical mechanisms of pain.
To know central mechanisms of nociceptive transmission/modulation: the spinal and medullary dorsal horns; segmental and brainstem pain modulation; thalamocortical mechanisms.

Work Placement(s)

No

Syllabus

The Nervous System: General principles and sensory physiology.
Basic functions of synapses and transmitting substances
The synapses: Types of synapses in the Central nervous system.
Synaptic contacts transmitters.
Electrical events during neuronal inhibition and excitation
Some special features in synaptic transmission
Central transmitters
Sensory receptors, neuronal circuits for information processing
Somatic sensations
Transmission Pathways.

Head Lecturer(s)

Marilia Assunção Rodrigues Ferreira Dourado

Assessment Methods

Assessment
Writing assessment test: 100.0%

Bibliography

Fisiopatologia da Dor, José M. Castro Lopes, Permanyer Portugal, 2003
Khalid S, Tubbs R (October 06, 2017) Neuroanatomy and Neuropsychology of Pain. Cureus 9(10): e1754.
DOI 10.7759/cureus.1754
Julius D, Basbaum AI, Molecular mechanisms of nociception. Nature 413: 203-210
October 2001Nature 413(6852):203-10; DOI: 10.1038/35093019