Pharmacology II

Recommended Prerequisites

Not applicable.

Teaching Methods

The teachin methods in this curricular unit include:

- Lectures

- Presentation and discussion of scientific articles

- Practical classes

- Seminars.

Learning Outcomes

Upon completion of this course unit, the student will be able to:
- Understand the basic mechanisms of drug action at the cellular and molecular level and their relation with cardiovascular, respiratory, nervous system and gastrointestinal diseases and cancer.
- Understand the various levels and methods used to identify the potential pharmacological activity of new molecules, characterize their mechanisms of action and evaluate their therapeutic potential.
- Apply the knowledge acquired to improve drug design.

Work Placement(s)

No

Syllabus

1. Neuropharmacology: neurotransmitter systems as pharmacological targets; antidepressants and stimulants of
the central nervous system; anxiolytics, sedatives and hypnotics; anti-psychotics; anti-epileptics; pharmacological
targets and therapeutic approaches in neurodegenerative diseases. Pharmacology of the antonomic nervous
system. Pharmacology of pain: opiod and nonopioid central analgesics; general and local anesthetics.
Inflammation and its chemical mediators: pharmacological targets a new antiinflammatory drugs.
2. Pharmacological targets and drugs that affect other organ systems: cardiovascular system, respiratory system, gastrointestinal tract, reproductive and urinary system and endocrine system.
3. Pharmacological targets and drugs used in the treatment of infections and cancer.

Head Lecturer(s)

Sónia Alexandra Pinto Ribeiro Silva Santos

Assessment Methods

Assessment continuous
Continuous evalvation (reports on the practical classes and seminars): 15.0%
Presentation an discussion of scientific articles: 20.0%
Exam: 65.0%

Bibliography

- RANG, Dale, Ritter & Flower. Rang & Dale's, Pharmacology. Churchill Livinstone, Elevier, 6th Edition, 2007. ISBN: 978-0-443-06911-6.

- BRUNTON, LL, Lazo JS, ParKer KL (eds.). Goodman & Gilman's. The Pharmacological Basis of Therapeutics. MrGraw-Hill, 11th Edition, 2006. ISBN: 0-07-142280-3

- NESTLER, EJ; Hyman, SE; Malenka, RC - Molecular Neuropharmacology: a fondation for clinical neurosciences. Mc Graw Hill Second edition, 2009. ISBN: 978-0-07-148127-4.

- Artigos científicos