Biochemistry

Recommended Prerequisites

Not applicable.

Teaching Methods

Not applicable.

Learning Outcomes

The main goal of this CU is the learning of the main metabolic mechanisms taking place within the human body, for
Medicinal Chemistry students, with previous knowledge of organic and inorganic chemistry, and structural biochemistry (acquired in the two first years of the course).
The students are expected to acquire skills on the cell function, at the molecular level – cellular dynamics and main
metabolic pathways - and their relationship with pathologic processes, as well as preventive and therapeutic strategies.

Work Placement(s)

No

Syllabus

1. Introduction
(Bioenergetics; metabolic characteristics of the main human organs and tissues)
2. Glycogen Metabolism
Clinical Correlations
3. Fatty Acid Metabolism
Clinical Correlations
4. Aminoacid Metabolism
Clinical Correlations
5. Functional Regulation of Nucleic Acids
Clinical Correlations
6. Metabolic Regulation
Clinical Correlations
7. Metabolic Impact of Drugs
Clinical Correlations.

Head Lecturer(s)

Maria Margarida Catalão Almiro e Castro

Assessment Methods

Evaluation
Project: 15.0%
Mini Tests: 30.0%
Exam: 55.0%

Bibliography

- “Biochemistry”, L. Stryer, J.M. Berg e J.L. Tymoczko, 7ª ed., Freeman, 2007.
- “Textbook of Biochemistry with Clinical Correlations”, 5ª ed., T.M. Devlin, Wiley, 2001.
- “General, Organic and Biochemistry”, K.J. Denniston, J.J. Topping e R.L. Caret, McGraw-Hill, 4ª ed., 2004.
- “Medical Cell Biology Made Memorable”, R.I. Norman e D. Lodwick, 1ª ed., Churchill Livingstone, 1999.
- “Lehninger Principles of Biochemistry”, 3ª ed., D.L. Nelson e M.M. Cox, Worth, 2000.
- “Organic and Biochemistry. Conecting Chemistry to your Life”, I. Blei e G. Odian, W.H. Freeman, 2000.