Biochemistry

Recommended Prerequisites

This course requires the prior acquisition of basic knowledge in Chemistry, Biology and Mathematics.

Teaching Methods

Lectures - the masterful type or presentation of clinical cases , supported by presentation slides and small interactive movies
Theoretical Practical - predominantly interactive and presentation of clinical cases , complemented by targeted investigation
Practical classes - with direct support two assistants in monitoring the practical work and covering :
1. Fundamental Concepts in Biochemistry
2. Research Methods major constituent of the cell
3. Application of biochemistry technology to Laboratory tests used in clinical Weekly availability for targeted study.

Learning Outcomes

1. Learn the biochemical mechanisms responsible for the homeostasis of the cell and the organism and its alteration in disease;
2. Know the biochemical processes responsible for the development , communication and control of cellular activity ;
3. Apply the knowledge acquired in solving clinical nature of problems , arousing their curiosity for biomedical research.

Work Placement(s)

No

Syllabus

1. Chemical composition of living beings
The main biomolecules 1.1
1.2 Water in biosystems
1.3 Balance Understanding Acid-Base
2. glucídico metabolism and oxidative
2.1 Structural and Functional Organization of carbohydrate
2.2 routes of synthesis and degradation
2.3 mitochondrial respiratory chain and oxidative phosphorylation
3. Lipid Metabolism
3.1 Structural and Functional Organization of lipids
3.2 routes of synthesis and degradation
3.3 Lipoproteins
4. Metabolism of nitrogen compounds
4.1 Structural and Functional Organization of proteins and nucleotides
4.2 Amino acids and their derivatives
4.3 Nucleotides
5. General Principles of regulation / metabolism modulation
5.1 Cell signaling and hormonal action
5.2 Vitamins
6. Biochemical characterization of cell
6.1 Muscle and bone cell
6.2 adipocyte
6.3 The nerve cell
7. Perspectives on biochemical disease
7.1 Biochemical mechanisms of degeneration
8. metabolic interrelationships
8.1 Metabolic Integration.

Head Lecturer(s)

Ana Cristina Carvalho Rego

Assessment Methods

Assessment
Other: continuous evaluation and practice: 30.0%
Exam: 70.0%

Bibliography

Biochemistry
Stryer L. W. H.
5th Edition – 2002
Freeman and Company. New York
Lippincotts Illustrated Review - Biochemistry
Richard Harvey and Denise Ferrier
5th Edition - 2010
Textbook of Biochemistry - With Clinical Correlations
Devlin T. M.
7th Edition - -2010
Wiley-Lyss, New York
Harper´s Biochemistry
Murray R., Granner D., Mays P. and Rodwell V.
28th Edition – 2009
Appleton and Lange, East Norwalk
Bioquímica – Organização Celular da Vida
Halpern, Manuel Júdice, Freire A. P. e Quintas A.
Edição de 2008
Lidel
Bioquímica
Halpern, Manuel Júdice
Edição de 1997
Lidel