Molecular Diagnosis

Recommended Prerequisites

All areas of life sciences (examples: Pharmaceutical Sciences, Medicine, Biochemistry or Biology).

Teaching Methods

Lectures: students actively engaged in the construction of knowledge, analysing diverse information in the context of Molecular Diagnosis. Links between a professional context and exploited scientific concepts will thus be established.

Autonomous learning: students will be encouraged to, autonomously get actively involved in the construction and development of their knowledge, searching and analysing information and solving problems, proposed (or not) by the teacher.

Problem-solving class: Presentation of papers selected within the themes of the lectures.

Learning Outcomes

Course whose main aim is to minister knowledge of the main methods of immunological and molecular diagnostics as well as the respective grounds for its use and application examples in research and clinical practice.

This course will allow students to gain skills for learning, integration and application of knowledge in the area of molecular diagnostics applied to human health and will contribute to enable students at the end of their training to:

• Perform basic and applied research in the biomedical field

• Perform the selection, use and evaluation of new methods of molecular diagnosis

Participate in the monitoring of clinical trials of new drugs and / or therapeutic strategies resulting from advanced technologies.

The implementation of the objectives described will enable students to develop the following skills: organization and planning; manage information; problem solving; critical thinking; autonomous learning; oral and written communication; concern for quality

Work Placement(s)

No

Syllabus

Biomarkers as early diagnosis tools for disorders associated with sleep deprivation; Molecular diagnosis of Hematological Diseases; Molecular diagnosis of bacterial infections: clinical cases; From cytogenetics to cytogenomics – the importance in diagnosis:; Molecular diagnosis; Molecular diagnosis in cancer ¸Molecular diagnosis of viral infections: the case of SARSCOV-2; Innovative and non-invasive ways of detecting cancer; Analytical diagnosis of hereditary metabolic diseases; Forensic Genetics; Preparation and presentation of biotechnological clippings; Genomics and Transcriptomics¸Preparation and presentation of work;

Head Lecturer(s)

Luís Maria Marques dos Santos Bimbo

Assessment Methods

Assessment
Exam: 40.0%
Other: 60.0%

Bibliography

Strachan, T and Read, A, Human Molecular Genetics 3, Garland Science, Taylor and Francis, London, 2003.

Klug, WS and Cummings MR, Concepts of Genetics 6th Ed. Prentice Hall, Inc., New Jersey, 20

Glick BR and Pasternak JJ, Molecular Biotechnology, Principles and Applications of Recombinant DNA (3rd edition), ASM Press, Washington, 2003.

Walsh, G, Biopharmaceuticals: Biochemistry and Biotechnology, John Wiley and Sons, New York, 2002.

Lima, N e Mota, M, Biotecnologia: Fundamentos e Aplicações, Lidel, Lisboa, 2003.

Videira, A, Engenharia genética. Princípios e Aplicações, Lidel, Lisboa, 2001.