Nephropathology in the Elderly

Recommended Prerequisites

Basic knowledge in anatomy and renal physiology; capacity for analysis and interpretation of the main basic clinical and analytical changes in renal disease; basic knowledge in English.

Teaching Methods

Lecture.

Learning Outcomes

Must know the anatomical and functional characteristics of normal kidney; should know and understand the main morphological and functional changes of the kidney in the elderly; should know and understand  the pathophysiological changes of the kidney in the elderly; must know to diagnose the functional changes of the kidney in the elderly; should know how to establish a plan for preventing the progression of kidney disease in the elderly with attention to diet and medication.

Work Placement(s)

No

Syllabus

Renal morphology and adaptation in the aging kidney;

Modifications of renal physiology with aging, structural and functional changes, clinical manifestations resulting from the aging process;

Study of renal function: The glomerular filtration rate and how to evaluate: creatinine / GFR correlation;

Theories of aging and biological mechanisms in the kidney; inhibitor mechanisms of progression of renal aging - drugs;

Major renal pathologies observed with advancing age;

The adjustment of the dosage of drugs to renal function.

Head Lecturer(s)

Rui Manuel Baptista Alves

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

Livro:
The aging kidney in health and disease
Machas-Núñez JF, J. Stewart Cameron and Dimitrios G. Oreopoulos
ed. Springer US, 2008
Capítulo de Livro
Patologia Nefrológica e envelhecimento.
Rui Alves
In: “Geriatria Fundamental – Saber e praticar”
ed. Lidel, 2014; cap. 21: 225-232.