Transposition Scale and Industrial Production of Drugs

Recommended Prerequisites

The recommended prerequisites include what is taught in the 1 st cycle courses in the area of Pharmacy, Medicine, Bioanalytical, Chemical Sciences or Engineering or, other courses considered appropriate by the FFUC Scientific Council.

Teaching Methods

Theoretical modules and practical examples.

Learning Outcomes

Provide students with a thorough overview of the project activities that precede the implementation of a new plant. Confer jurisdiction at different stages of the preliminary analysis of implementation of a new production unit in particular required in Market Analysis, the use of international databases, development of mass balances and energy, the choice and use of industrial utilities and analysing economic viability of the investment.

Work Placement(s)

No

Syllabus

Market analysis. Estimation of Future Search. Query databases (Eurostat). Fixing capacity of a production unit. Plant location. Critical analysis of manufacturing technologies and selection process. Diagram and Process Specification Sheets.
Economic evaluation of industrial projects. Investment calculation. Production Cost. The return on investment.
Mass balance in steady state. Mechanical separation process. Chemical and biological reactions. Limiting reactant, conversion, selectivity and yield. Mass balance of the process with by-pass, recycling and purge.
Generic equation of energy balance. Reference state. Heat capacity of gas, liquid and solids. Enthalpy calculation. Phase Change operations. Mixing and solution. Thermal Fluid: thermodynamic tables. Calculation of the heat of reaction. Batch processes, number of annual cycles. Balances on transient non-reactive processes.

Head Lecturer(s)

Anthony Joseph Burke

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

“Plant design and Economics for Chemical Engineers”, M.S. Peters and K.D Timmerhaus, 5ª Ed. Ed Mc. Graw-Hill, 2004.
“Elementary Principles of Chemical Processes”, R. M. Felder e R. W. Rousseau, 3ª Ed., John Wiley, New York, 2000
“Bioprocess Engineering Principles”, P. M. Doran, 2ª Ed., Academic Press, New York, 2013
“Basic Principles and Calculations in Chemical Engineering”, D. M. Himmelblau, 6ª Ed., Prentice Hall PTR, New Jersey, 1996
“Process Design Principles”, W.D. Seider, J.D Seader, D.R. Lewin, 1ª Ed., John Wiley, New York, 1999
“Analysis, Synthesis and Design of Chemical Processes”, R. Turton, R.C. Bailie, W.B. Whiting, J.A. Shaeiwitz, Prentice Hall PTR, New Jersey, 1998.