Physiopathology and Therapeutics I

Recommended Prerequisites

Anatomy, Physiology, pharmacology and histology; Microbiology and Parasitology, Immunology, and Genetics.

Teaching Methods

Theoretical classes:
• Prior assessment of students’ level of knowledge.
• Formulation of objectives.
• Clarification of questions that promote reasoning.
• Group discussion
• Discussion that allows a post-lecture assessment.
• Lecturing complemented by a brief final summary.
Practical lessons:
• Analysis of documents.
• Presentations carried out by students.
• Experiential learning.

Learning Outcomes

The main objective: To study the disease and its therapeutic bases in a scientific approach.
General Objectives:
1. To study the general aggression and defence mechanisms of the human body;
2. To study the pathological processes/mechanisms that form the basis of diseases;
3. To provide students with general matters, therapeutic bases
4. To study recent forms of therapeutic approach for each Nosological entity, more frequent.
  • Explain the pathophysiological processes of the different agents of disease: mechanical agents, thermoregulation, radiation/electricity, chemicals, living agents, environmental allergens
  • Know the main mechanisms of the host response to aggression: inflammation, fever, edema, electrolyte changes, pain, stress, cancer. Demonstrate the capability of identifying the different etiopathogenic parameters. Evaluate laboratory parameters of the inflammatory response.

Work Placement(s)

No

Syllabus

General notions and scope of Pathophysiology/pathology/therapeutics
Basis for the study of disease.
homeostasis; normal versus usual; health; disease and quality of life
Etiology, pathogenesis. Diagnosis,prognosis. Nosography,Nosology. Patocronia.
Semiology
Climatic influences, geographical, racial and social health and illness of populations
Pharmacogenetics – General notions
Causes of the diseases
Antibiotics, antiviral, anti-parasitic and antitóxicos ,Its therapeutic applications
Pathophysiology of fever
Antipyretics: mechanisms of action, bioavailability, interactions.
Pathophysiology of sensitivity and Pain
Pathophysiology of stress.
Modifiers of the psyche and the immune system and stress management.
Pathophysiology of circulatoy system
Anti-hypertension Anti-anginosos and anticoagulants
Pathophysiology of cancer
Cancer treatment conventional and new drugs target.

Head Lecturer(s)

Marilia Assunção Rodrigues Ferreira Dourado

Assessment Methods

Assessment
Exam: 100.0%

Bibliography

J. García-Conde. Patología General - Semiología Clínica y Fisiopatología. Editora: McGraw-Hill – Interamericana; Madrid 2004
The Pharmacological Basis of Therapeutics. Goodman and Gilman, 2009, MacGrawHill
Mota-Pinto, A. Fisiopatologia – Fundamentos e Aplicações. 1. ed. Lisboa: Lidel, Edições Técnicas, 2007 Copyright © Outubro de 2007/Reimpressão – Janeiro de 2009/ 2ª edição revista em 2013 Bibliografia apropriada, a recomendar e/ou fornecer, para temas específicos.
O material didático utilizado nas aulas (diapositivos, artigos) será disponibilizado aos alunos.