Drugs and Medicinal Products
2
2023-2024
01551259
HEALTH SCIENCES AND TECHNOLOGIES
Portuguese
Face-to-face
SEMESTRIAL
3.0
Compulsory
1st Cycle Studies
Recommended Prerequisites
Relevant curricular units:
- Celular Biology (1st Y/ 1st S);
- Molecular Biology (1st Y/ 2nd S);
- Human Anatomy and Physiology I (2nd Y/ 1st S);
- Biochemistry (2nd Y/ 1st S);
- Laboratory Methodologies (1st Y/1st S)
- Analytical Chemistry (1st Y/2nd S)
- Instrumental Analysis (2nd Y/1st S)
Recommended foundation knowledge:
- Biological systems general functioning;
- Human anatomy and pathophysiology;
- General chemistry and biochemistry;
- General laboratory materials, equipment, conduct and procedures.
Teaching Methods
- Aulas expositivas (teóricas), lecionadas em formato de palestra, mas com indução para a participação ativa dos alunos, incluindo o estímulo do pensamento crítico;
- Aulas práticas laboratoriais.
Learning Outcomes
- To learn essencial concepts related to drug administration: pharmacology, pharmacokinetics, and pharmaceutical technology;
- To have a general vision on pharmaceutical development;
- To know the importance of pre-formulation studies;
- To dominate aspects related to the production of pharmaceutical dosage forms, including their definition, preparation, formulation, and specific problems related to each type.
Work Placement(s)
NoSyllabus
- Pharmacology and pharmacokinetics;
- Pharmaceutical development - general concepts;
- Pre-formulation studies;
- Solid dosage forms: powders, pellets, pills and capsules;
- Homogeneous dispersed systems: solutions and syrups;
- Heterogeneous dispersed systems: suspensions, solutions, and colloidal systems;
- Semisolid preprations.
Head Lecturer(s)
Patrícia Sofia Cabral Pires
Assessment Methods
Assessment
Practical-laboratory exam: 25.0%
Frequency: 75.0%
Bibliography
Aulton's Pharmaceutics: The Design and Manufacture of Medicines, 4th edition, Churcill Livingstone, M. E. Aulton (Ed.), Kevin M. G. Taylor, 2013
Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form, Informa Healthcare Press, Mark Gibson (Ed.), 2009
Swarbrick, J. and Boylan, J.C., Encyclopedia of Pharmaceutical Technology, Marcel Dekker, Inc. New York . Basel, 1990
Nogueira Prista, L., Correia Alves, A. e Rui Morgado (com a colaboração de Sousa Lobo, J.M.), Tecnologia Farmacêutica, I, II e III Volumes, Fundação Calouste Gulbenkian, Lisboa, 5ª Ed., 1995
Kibbe, A.H., Handbook of Pharmaceutical Excipients, American Pharmaceutical Association and Pharmaceutical Press, Washington, DC . London, 3ª Ed., 2000
Lachman, L., Lieberman, H.A. and Kaning, J.L. (tradução Pinto, J.F. e Fernandes, A.I.), Teoria e Prática na Indústria Farmacêutica, Volume I e II, Fundação Calouste Gulbenkian, Lisboa, 2001