Advanced Instrumental Methods of Analysis

Recommended Prerequisites

Not applicable.

Teaching Methods

Lectures, laboratorial demonstrations/laboratorial work.

Learning Outcomes

The course aims to provide solid knowledge in advanced methods of analysis which find wide application in quality control, in industrial and research laboratories, in environmental monitoring.

Work Placement(s)

No

Syllabus

GC-MS. ionization sources, EI. CI: PICI and NICI; HPLC-MS, interfaces APCI, APPI, ESI. Mass analyzers. Signal acquisition methods, full scan, SIM. TIC, XIC. Quantitative analysis. Internal standard
Tandem MS. Space configuration. CID. Operation modes.
Molecular absorption ultraviolet-visible spectroscopy, diffuse reflectance. UV/VIS microspectroscopy. Infrared spectroscopy, ATR, DRIFTS. Infrared and Raman microspectroscopies.
Atomic absorption spectroscopy, AAS. Flame and graphite furnace atomization. Cold vapor and hydride generation. HR-CS AAS - high resolution continuous source AAS
Atomic emission spectroscopy. ICP-OES. Laser ablation
Atomic mass spectrometry. ICP-MS. Interferences. Reaction and collision dynamic cells. Isotopic dilution method
Thermal methods of analysis.
X-ray fluorescence
Scanning electron microscopy
Atomic force microscopy
Electrochemical methods. Voltammetric methods. Potentiometric methods.
Electroanalysis. Electrochemical sensors.

Assessment Methods

Assessment
Laboratory work or Field work: 30.0%
Exam: 70.0%

Bibliography

Principles of Instrumental Analysis, PF. Holler,  D. Skoog, S. Crouch, , 7th ed.,  Cengage Learning, Inc, Mason, 2017.

Analytical Atomic Spectrometry with Flames and Plasmas, J. A. C. Broekaert,  Wiley-VCH, Weinheim, 2002.

The Essence of Chromatography, C. F. Poole, Elsevier, Amsterdam, 2003.

Principles and Applications of Thermal Analysis, Paul Gabbott, Blackwell Publising, Oxford, 2008.

Practical Instrumental Analysis, S. Petrozzi, Wiley-VCH, Weinheim, 2013.

Modern Instrumental Analysis,  S. Ahuja, N. Jespersen (eds.),in Comprehensive Analytical Chemistry, D. Barceló (ed.) vol. 47, Elsevier, Amsterdam, 2006.

Electroquímica. Princípios, Métodos e Aplicações C.M.A. Brett e A.M. Oliveira Brett,  Livraria Almedina, Coimbra, 1996.

Electroanalysis C.M.A. Brett e A.M. Oliveira Brett, Oxford University Primers Nº 64, Oxford, 1998.

Laboratory techniques in electroanalytical chemistry P.T. Kissinger e W.R. Heineman Ed., Dekker, NY, 1996.